STRUCTURAL BIOLOGY Tracing Argonaute binding

被引：11

作者：

Bouasker, Samir ^{[1
]}

Simard, Martin J. ^{[1
]}

机构：

[1] Univ Laval, Canc Res Ctr, Hotel Dieu Quebec, Quebec City, PQ G1R 2J6, Canada

来源：

NATURE | 2009年 / 461卷 / 7265期

关键词：

SILENCING COMPLEX; CRYSTAL-STRUCTURE; RNA; DNA;

D O I：

10.1038/461743a

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Argonaute proteins inhibit gene expression by binding to messenger RNA via a small nucleic-acid guide. Structures of the Argonaute complex bound to target RNA reveal snapshots of a silencing machine at work.

引用

页码：743 / 744

页数：2

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