Sparse representation in the human medial temporal lobe

被引:118
作者
Waydo, Stephen
Kraskov, Alexander
Quiroga, Rodrigo Quian
Fried, Itzhak
Koch, Christof
机构
[1] CALTECH, Control & Dunam Syst, Pasadena, CA 91125 USA
[2] CALTECH, Computat & Neural Syst, Pasadena, CA 91125 USA
[3] Univ Leicester, Dept Engn, Leicester LE1 7RH, Leics, England
[4] Univ Calif Los Angeles, Div Neuropsychiat, Los Angeles, CA 90095 USA
[5] Univ Calif Los Angeles, Inst Neuropsychiat, Los Angeles, CA 90095 USA
[6] Tel Aviv Univ, Sackler Fac Med, Funct Neurosurg Unit, IL-69978 Tel Aviv, Israel
关键词
representation; sparseness; MTL; hippocampus; memory; neural coding;
D O I
10.1523/JNEUROSCI.2101-06.2006
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Recent experiments characterized individual neurons in the human medial temporal lobe with remarkably selective, invariant, and explicit responses to images of famous individuals or landmark buildings. Here, we used a probabilistic analysis to show that these data are consistent with a sparse code in which neurons respond in a selective manner to a small fraction of stimuli.
引用
收藏
页码:10232 / 10234
页数:3
相关论文
共 19 条
[1]  
[Anonymous], 1967, INTEGRATIVE ACTIVITY
[2]  
Barlow H B, 1972, Perception, V1, P371, DOI 10.1068/p010371
[3]   RECOGNITION-BY-COMPONENTS - A THEORY OF HUMAN IMAGE UNDERSTANDING [J].
BIEDERMAN, I .
PSYCHOLOGICAL REVIEW, 1987, 94 (02) :115-147
[4]   Single neuron activity in human hippocampus and amygdala during recognition of faces and objects [J].
Fried, I ;
MacDonald, KA ;
Wilson, CL .
NEURON, 1997, 18 (05) :753-765
[5]   Genealogy of the "grandmother cell" [J].
Gross, CG .
NEUROSCIENTIST, 2002, 8 (05) :512-518
[6]   Variation in hippocampal neuron number with age and brain volume [J].
Harding, AJ ;
Halliday, GM ;
Kril, JJ .
CEREBRAL CORTEX, 1998, 8 (08) :710-718
[7]   Intracellular features predicted by extracellular recordings in the hippocampus in vivo [J].
Henze, DA ;
Borhegyi, Z ;
Csicsvari, J ;
Mamiya, A ;
Harris, KD ;
Buzsáki, G .
JOURNAL OF NEUROPHYSIOLOGY, 2000, 84 (01) :390-400
[8]   SPARSELY CODED ASSOCIATIVE MEMORIES - CAPACITY AND DYNAMIC PROPERTIES [J].
MEUNIER, C ;
YANAI, HF ;
AMARI, S .
NETWORK-COMPUTATION IN NEURAL SYSTEMS, 1991, 2 (04) :469-487
[9]   Sparse coding of sensory inputs [J].
Olshausen, BA ;
Field, DJ .
CURRENT OPINION IN NEUROBIOLOGY, 2004, 14 (04) :481-487
[10]   Invariant visual representation by single neurons in the human brain [J].
Quiroga, RQ ;
Reddy, L ;
Kreiman, G ;
Koch, C ;
Fried, I .
NATURE, 2005, 435 (7045) :1102-1107