A computer model of lung morphology to analyze SPECT images

被引：20

作者：

Schroeter, JD ^{[1
]}

Fleming, JS ^{[1
]}

Hwang, DM ^{[1
]}

Martonen, TB ^{[1
]}

机构：

[1] US EPA, Natl Hlth & Environm Effects Res Lab, Expt Toxicol Div, Res Triangle Pk, NC 27711 USA

来源：

COMPUTERIZED MEDICAL IMAGING AND GRAPHICS | 2002年 / 26卷 / 04期

关键词：

lung morphology; computer simulation; single photon emission computed tomography analysis; aerosol deposition; airway quantification;

D O I：

10.1016/S0895-6111(02)00014-9

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Measurement of the spatial distribution of aerosol deposition in human lungs can be performed using single photon emission computed tomography (SPECT). To relate deposition patterns to real lung structures, a computer model of the airway network has been developed. Computer simulations are presented that are compatible with the analysis of SPECT images. Computational techniques that are consistent with clinical procedures are used to analyze airways by type and number within transverse slices of the lung volume. The computer models serve as customized templates, which when analyzed alongside gamma scintigraphy images, can assist in the interpretation of human test data. Published by Elsevier Science Ltd.

引用

页码：237 / 246

页数：10

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