Maternal Serum Analyte Screening for Fetal Aneuploidy

被引:1
作者
Chasen, Stephen T. [1 ,2 ]
机构
[1] New York Presbyterian Hosp, New York, NY USA
[2] Weill Cornell Med Coll, New York, NY 10021 USA
关键词
serum screening; fetal aneuploidy; Down syndrome; HUMAN CHORIONIC-GONADOTROPIN; FREE BETA-HCG; PLASMA PROTEIN-A; ALPHA-FETOPROTEIN; DOWN-SYNDROME; 1ST TRIMESTER; PAPP-A; NUCHAL TRANSLUCENCY; TWIN PREGNANCIES; 2ND-TRIMESTER;
D O I
10.1097/GRF.0000000000000017
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
In the first and second trimesters, chemicals produced by the fetoplacental unit are measured to assess risks of fetal abnormalities. Consistent associations between levels of these proteins in such pregnancies enable these biomarkers to be used to calculate risk for Down syndrome and other chromosomal abnormalities in individual pregnancies. Special consideration may be required when assessing risk in multiple pregnancies and pregnancies achieved with infertility therapy.
引用
收藏
页码:182 / 188
页数:7
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