Life at the end of the chromosome: Telomeres and telomerase

被引：0
作者：
Cech, TR [1 ]
机构：
[1] Univ Colorado, Howard Hughes Med Inst, Dept Chem & Biochem, Boulder, CO 80309 USA
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2000年 / 39卷 / 01期
关键词：
enzymes; ribonucleoprotein; RNA; telomerase; telomere; tumor therapy;
D O I：
10.1002/(SICI)1521-3773(20000103)39:1<34::AID-ANIE34>3.0.CO;2-N
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
引用
收藏
页码：34 / 43
页数：10
相关论文
共 73 条
[1]  
[Anonymous], 1995, Telomeres
[2]   Telomerase activity: A biomarker of cell proliferation, not malignant transformation [J].
Belair, CD ;
Yeager, TR ;
Lopez, PM ;
Reznikoff, CA .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (25) :13677-13682
[3]   TANDEMLY REPEATED SEQUENCE AT TERMINI OF EXTRACHROMOSOMAL RIBOSOMAL-RNA GENES IN TETRAHYMENA [J].
BLACKBURN, EH ;
GALL, JG .
JOURNAL OF MOLECULAR BIOLOGY, 1978, 120 (01) :33-53
[4]   Extension of life-span by introduction of telomerase into normal human cells [J].
Bodnar, AG ;
Ouellette, M ;
Frolkis, M ;
Holt, SE ;
Chiu, CP ;
Morin, GB ;
Harley, CB ;
Shay, JW ;
Lichtsteiner, S ;
Wright, WE .
SCIENCE, 1998, 279 (5349) :349-352
[5]   Telomerase and the maintenance of chromosome ends [J].
Bryan, TM ;
Cech, TR .
CURRENT OPINION IN CELL BIOLOGY, 1999, 11 (03) :318-324
[6]   Telomerase reverse transcriptase genes identified in Tetrahymena thermophila and Oxytricha trifallax [J].
Bryan, TM ;
Sperger, JM ;
Chapman, KB ;
Cech, TR .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (15) :8479-8484
[7]   Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines [J].
Bryan, TM ;
Englezou, A ;
DallaPozza, L ;
Dunham, MA ;
Reddel, RR .
NATURE MEDICINE, 1997, 3 (11) :1271-1274
[8]  
Cech T R, 1997, Ciba Found Symp, V211, P20
[9]  
Chapon C, 1997, RNA, V3, P1337
[10]   TETRAHYMENA TELOMERASE CATALYZES NUCLEOLYTIC CLEAVAGE AND NONPROCESSIVE ELONGATION [J].
COLLINS, K ;
GREIDER, CW .
GENES & DEVELOPMENT, 1993, 7 (7B) :1364-1376
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