Whole Body 18F-FDG PET/CT Imaging in the Detection of Primary Tumours in Patients with a Metastatic Carcinoma of Unknown Origin

被引：0

作者：

Kaya, Ali Osman ^{[1
,2
,3
]}

Coskun, Ugur ^{[1
,2
,3
]}

Unlu, Mustafa ^{[1
,2
,3
]}

Akdemir, Umit Ozgur ^{[1
,2
,3
]}

Ozdemir, Nuriye Yildirim ^{[1
,2
,3
]}

Zengin, Nurullah ^{[1
,2
,3
]}

Benekli, Mustafa ^{[1
,2
,3
]}

Yildiz, Ramazan ^{[1
,2
,3
]}

Yaman, Emel ^{[1
,2
,3
]}

Ozturk, Banu ^{[1
,2
,3
]}

Gumus, Mahmut ^{[1
,2
,3
]}

Uner, Aytug ^{[1
,2
,3
]}

Yamac, Deniz ^{[1
,2
,3
]}

Ucgul, Emel ^{[1
,2
,3
]}

Buyukberber, Suleyman ^{[1
,2
,3
]}

机构：

[1] Gazi Univ, Sch Med, Dept Med Oncol, Istanbul, Turkey

[2] Ankara Numune Training & Res Hosp, Dept Nucl Med, Istanbul, Turkey

[3] Istanbul Kartal Educ & Res Hosp, Dept Med Oncol, Istanbul, Turkey

来源：

ASIAN PACIFIC JOURNAL OF CANCER PREVENTION | 2008年 / 9卷 / 04期

关键词：

Carcinoma of unknown primary; CUP; 18F-FDG PET/CT; survival;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Purpose: The aim of this study was to evaluate the role of whole body 18F-FDG PET/CT imaging in the detection of primary tumors in patients with a metastatic cancer from an unknown primary site. Methods: The study population consisted of 43 patients with a biopsy proven metastatic disease, negative conventional diagnostic procedures (including CT/MRI/endoscopic procedures) and a whole body 18F-FDG PET/CT examination. Patients' records were retrospectively analyzed. According to the final pathologic diagnoses, rate of detection of the primary tumor site was determined. Additionally, overall patient survival was calculated to evaluate the prognostic value of 18F-FDG PET/CT findings. Results: A primary tumor site was shown by 18F-FDG PET/CT in 24 patients (24/43; 55.8%). In 18 patients 18F-FDG PET/CT scans were negative (18/43; 41.8%). In a patient with an adenocarcinoma metastasis 18F-FDG PET/CT was falsely positive for an inflammatory lesion in the lung. Among the 18F-FDG PET/CT positive and negative groups median overall survival was not significantly different (log-rank p=0.573). Conclusion: Whole body 18F-FDG PET/CT imaging has a high rate of detection of a primary tumor in patients with a carcinoma of unknown origin.

引用

页码：683 / 686

页数：4

共 21 条

[1] ANALYSIS OF A DIAGNOSTIC STRATEGY FOR PATIENTS WITH SUSPECTED TUMORS OF UNKNOWN ORIGIN [J].