Venous thromboembolism is a product in proliferation of cancer cells

被引:0
|
作者
Wang, Le-Min [1 ]
Duan, Qiang-Lin [1 ]
Yi, Xiang-Hua [2 ]
Zeng, Yu [2 ]
Gong, Zhu [1 ]
Yang, Fan [3 ]
机构
[1] Tongji Univ, Sch Med, Dept Cardiol, Tongji Hosp, Shanghai 200065, Peoples R China
[2] Tongji Univ, Sch Med, Dept Pathol, Tongji Hosp, Shanghai 200065, Peoples R China
[3] Tongji Univ, Sch Med, Dept Lab Med, Tongji Hosp, Shanghai 200065, Peoples R China
来源
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE | 2014年 / 7卷 / 05期
关键词
Venous thromboembolism; cancer; filter; PULMONARY-EMBOLISM; THROMBOSIS;
D O I
暂无
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
The pathogenesis of venous thromboembolism (VTE) in patients with cancer is related to the destruction of small veins and the intravenous formation of filamentous mesh-like structure by fibrinogen. The filamentous mesh-like filter can block hematogenous metastasis of cancer cells and also can stagnate blood cells, leading to venous thrombosis. Cancer cells have characteristics of malignancy and fast proliferation, and ischemic necrosis frequently occurs, and small veins were invaded and damaged. The formation of filamentous mesh-like structure has defense function and also may cause the occurrence of VTE. VTE is a product of the proliferation process of malignant cells.
引用
收藏
页码:1319 / 1323
页数:5
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