68Ga-DOTATOC PET-CT in the localization of source of ectopic ACTH in patients with ectopic ACTH-dependent Cushing's syndrome

被引：27

作者：

Venkitaraman, Balasubramanian ^{[1
]}

Karunanithi, Sellam ^{[2
]}

Kumar, Arvind ^{[1
]}

Bal, Chandrasekhar ^{[2
]}

Ammini, Ariachery C. ^{[3
]}

Kumar, Rakesh ^{[2
]}

机构：

[1] All India Inst Med Sci, Dept Surg Disciplines, New Delhi, India

[2] All India Inst Med Sci, Dept Nucl Med, New Delhi, India

[3] All India Inst Med Sci, Dept Endocrinol, New Delhi, India

来源：

CLINICAL IMAGING | 2014年 / 38卷 / 02期

关键词：

Ectopic ACTH-dependent Cushing's syndrome; Ga-68-DOTATOC; PET-CT; Neuroendocrine tumors; ADRENOCORTICOTROPIC HORMONE-SECRETION; DIFFERENTIAL-DIAGNOSIS; NEUROENDOCRINE TUMORS; PULMONARY CARCINOIDS; EXPERIENCE; CANCER;

D O I：

10.1016/j.clinimag.2013.10.007

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Localization of the source of adrenocorticotrophic hormone (ACTH) in ectopic ACTH-induced Cushing's syndrome is of paramount importance as definitive management mainly involves surgical resection of tumor. Many of these are occult, not identified by conventional structural imaging. Accurate localization and assessment of their functional status has become feasible with the use positron emission tomographycomputerized tomography using Ga-68-DOTATOC (1,4,7,10-tetraazacy-dododecane-NLNILNIILNIIII-tetraacetic acid(D)-Phel-thy3-octreotide), aiding in proper planning for their definitive management. (C) 2014 Elsevier Inc. All rights reserved.

引用

页码：208 / 211

页数：4

共 14 条

[1] Comparison between 68Ga-DOTA-NOC and 18F-DOPA PET for the detection of gastro-entero-pancreatic and lung neuro-endocrine tumours [J].

Ambrosini, Valentina ;

Tomassetti, Paola ;

Castellucci, Paolo ;

Campana, Davide ;

Montini, Giancarlo ;

Rubello, Domenico ;

Nanni, Cristina ;

Rizzello, Anna ;

Franchi, Roberto ;

Fanti, Stefano .

EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2008, 35 (08) :1431-1438

[2] 68Ga-DOTA-NOC: a new PET tracer for evaluating patients with bronchial carcinoid [J].

Ambrosini, Valentina ;

Castellucci, Paolo ;

Rubello, Domenico ;

Nanni, Cristina ;

Musto, Alessandra ;

Allegri, Vincenzo ;

Montini, Gian Carlo ;

Mattioli, Sandro ;

Grassetto, Gaia ;

Al-Nahhas, Adil ;

Franchi, Roberto ;

Fanti, Stefano .

NUCLEAR MEDICINE COMMUNICATIONS, 2009, 30 (04) :281-286

[3] Cushing syndrome due to ectopic adrenocorticotropic hormone secretion [J].

Aniszewski, JP ;

Young, WF ;

Thompson, GB ;

Grant, CS ;

van Heerden, JA .

WORLD JOURNAL OF SURGERY, 2001, 25 (07) :934-940

[4] Cushing Syndrome Secondary to Ectopic Adrenocorticotropic Hormone Secretion The University of Texas MD Anderson Cancer Center Experience [J].

Ejaz, Shamim ;

Vassilopoulou-Sellin, Rena ;

Busaidy, Naifa L. ;

Hu, Mimi I. ;

Waguespack, Steven G. ;

Jimenez, Camilo ;

Ying, Anita K. ;

Cabanillas, Maria ;

Abbara, Maher ;

Habra, Mouhammed Amir .

CANCER, 2011, 117 (19) :4381-4389

[5] Cushing's syndrome due to ectopic corticotropin secretion: Twenty years' experience at the National Institutes of Health [J].

Ilias, I ;

Torpy, DJ ;

Pacak, K ;

Mullen, N ;

Wesley, RA ;

Nieman, LK .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2005, 90 (08) :4955-4962

[6] Evaluation of the role of [18F]FDG-PET/CT and [68Ga]DOTATOC-PET/CT in differentiating typical and atypical pulmonary carcinoids [J].

Jindal, Tarun ;

Kumar, Arvind ;

Venkitaraman, Balasubramanian ;

Meena, Monika ;

Kumar, Rakesh ;

Malhotra, Arun ;

Dutta, Roman .

CANCER IMAGING, 2011, 11 (01) :70-75

[7]

Jindal Tarun, 2010, Korean Journal of Internal Medicine, V25, P386, DOI 10.3904/kjim.2010.25.4.386

[8] Functional Imaging of neuroendocrine tumors with combined PET/CT using 68Ga-DOTATATE (Dota-DPhe1,Tyr3-octreotate) and 18F-FDG [J].

Kayani, Irfan ;

Bomanji, Jamshed B. ;

Groves, Ashley ;

Conway, Gerard ;

Gacinovic, Sveto ;

Win, Thida ;

Dickson, John ;

Caplin, Martyn ;

Ell, Peter Joseph .

CANCER, 2008, 112 (11) :2447-2455

[9] Differential diagnosis and imaging in Cushing's syndrome [J].

Lindsay, JR ;

Nieman, LK .

ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA, 2005, 34 (02) :403-+

[10] PETROSAL SINUS SAMPLING WITH AND WITHOUT CORTICOTROPIN-RELEASING HORMONE FOR THE DIFFERENTIAL-DIAGNOSIS OF CUSHINGS-SYNDROME [J].

OLDFIELD, EH ;

DOPPMAN, JL ;

NIEMAN, LK ;

CHROUSOS, GP ;

MILLER, DL ;

KATZ, DA ;

CUTLER, GB ;

LORIAUX, DL .

NEW ENGLAND JOURNAL OF MEDICINE, 1991, 325 (13) :897-905

← 1 2 →