A novel Zn2+ complex as the ratiometric two-photon fluorescent probe for biological Cd2+ detection

被引：27

作者：

Ye, Weipeng ^{[1
]}

Wang, Shuxing ^{[1
]}

Meng, Xiangming ^{[1
]}

Feng, Yan ^{[1
]}

Sheng, Hongting ^{[1
]}

Shao, Zonglong ^{[1
]}

Zhu, Manzhou ^{[1
]}

Guo, Qingxiang ^{[2
]}

机构：

[1] Anhui Univ, Sch Chem & Chem Engn, Hefei 230601, Peoples R China

[2] Univ Sci & Technol China, Dept Chem, Hefei 230026, Peoples R China

来源：

DYES AND PIGMENTS | 2014年 / 101卷

关键词：

Ratiometic; Two-photon; Fluorescent probe; Zn2+ complex; Cd2+; Bio-imaging; AQUEOUS-SOLUTION; LIVING CELLS; CADMIUM; SENSOR; ZINC; CHEMOSENSOR; MICROSCOPY; MOLECULE; DESIGN; WATER;

D O I：

10.1016/j.dyepig.2013.09.013

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A novel Zn2+ complex as the ratiometric two-photon fluorescent probe (HQZn) for Cd2+ detection was synthesized. Fluorescence emission spectra of the probe showed a large red-shift (75 nm) and obvious enhancement of fluorescent intensity upon the addition of Cd2+. HQZn shows high selectivity for Cd2+ over other metal ions, and can eliminate the interference of Zn2+ during Cd2+ detection. Maldi-TOF MS spectra indicated that the response of HQZn to Cd2+ was caused by central metal displacement. Cell cytotoxicity and bio-imaging studies revealed that HQZn was cell-permeable and it could be used to detect intracellular Cd2+ with low cytotoxicity under two-photon excitation. (C) 2013 Elsevier Ltd. All rights reserved.

引用

页码：30 / 37

页数：8

共 39 条

[1] Two-photon fluorescence excitation cross sections of biomolecular probes from 690 to 960 nm [J].

Albota, MA ;

Xu, C ;

Webb, WW .

APPLIED OPTICS, 1998, 37 (31) :7352-7356

[2] A turn-on fluorescent sensor for Zn(II) based on fluorescein-coumarin conjugate [J].

An, Jun-mei ;

Yan, Mi-hui ;

Yang, Zheng-yin ;

Li, Tian-rong ;

Zhou, Qiao-xia .

DYES AND PIGMENTS, 2013, 99 (01) :1-5

[3] Flow injection on-line hydrophobic sorbent extraction for flame atomic absorption spectrometric determination of cadmium in water samples [J].

Anthemidis, Aristidis N. ;

Karapatouchas, Christos-Paraskevas P. .

MICROCHIMICA ACTA, 2008, 160 (04) :455-460

[4] A highly sensitive and selective ratiometric Cd2+ fluorescent sensor for distinguishing Cd2+ from Zn2+ based on both fluorescence intensity and emission shift [J].

Bao, Yinyin ;

Liu, Bin ;

Wang, Hu ;

Du, Fanfan ;

Bai, Ruke .

ANALYTICAL METHODS, 2011, 3 (06) :1274-1276

[5] A quinoline based fluorescent probe that can distinguish zinc(II) from cadmium(II) in water [J].

Cai, Yulei ;

Meng, Xiangming ;

Wang, Shuxin ;

Zhu, Manzhou ;

Pan, Zhongwen ;

Guo, QingXiang .

TETRAHEDRON LETTERS, 2013, 54 (09) :1125-1128

[6] Two-Photon Fluorescent Probes of Biological Zn(II) Derived from 7-Hydroxyquinoline [J].

Chen, Xiao-Yun ;

Shi, Jing ;

Li, Yi-Ming ;

Wang, Feng-Liang ;

Wu, Xu ;

Guo, Qing-Xiang ;

Liu, Lei .

ORGANIC LETTERS, 2009, 11 (19) :4426-4429

[7] A Highly Sensitive and Selective OFF-ON Fluorescent Sensor for Cadmium in Aqueous Solution and Living Cell [J].

Cheng, Tanyu ;

Xu, Yuifang ;

Zhang, Shenyi ;

Zhu, Weiping ;

Qian, Xuhong ;

Duan, Liping .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2008, 130 (48) :16160-+

[8] A highly selective "turn-on" fluorescent chemosensor based on hydroxy pyrene-hydrazone derivative for Zn2+ [J].

Choi, Ji Young ;

Kim, Dabin ;

Yoon, Juyoung .

DYES AND PIGMENTS, 2013, 96 (01) :176-179

[9] Pd(quinoline-8-carboxylate)2 as a low-priced, phosphine-free catalyst for heck and suzuki reactions [J].

Cui, Xin ;

Li, Juan ;

Zhang, Zhi-Ping ;

Fu, Yao ;

Liu, Lei ;

Guo, Qing-Xiang .

JOURNAL OF ORGANIC CHEMISTRY, 2007, 72 (24) :9342-9345

[10] 2-PHOTON LASER SCANNING FLUORESCENCE MICROSCOPY [J].

DENK, W ;

STRICKLER, JH ;

WEBB, WW .

SCIENCE, 1990, 248 (4951) :73-76

← 1 2 3 4 →