Human beings are mainly composed of different cells / tissues / organs which carry out various physiological roles representing a complex functional system. Now a days, it is difficult to predict the interactions between organs, including cells or tissues using in vitro cell culture approaches, as a result, animal tests should be conducted, pertaining to predict pharmacokinetics. So, major challenges as given through implantable technologies except the biomedical arena, showed some ignorance in mid-1990s. Few scientists have claimed some benefits about the usage of these medical-related technologies to patients, who have suffer from curable diseases or illnesses. Even today, scientists argue that this technology can be dangerous for the society at large, if applied incorrectly. Now, chip based technology has taken over the last few years. Various uses of microchips are applied especially in the field of medicine and human health care as well. The major benefits for this technology are reduced costs, low sample volumes, ease of use and precise results. This technology is to be used extensively in point-of-care diagnostics in less-developed countries. These chip based devices should be applied and are used to observe continuous or linked through various pharmacokinetics or immuno biological processes such as absorption, distribution, excretion, metabolism of various drug administration routes. Microchip technologies have all been expanded very rapidly and are coupled with various types of detection techniques which may be suitable especially for high-throughput screening including detection and mechanistic study of drugs. In this review article, we have discussed the importance and need of microchip technology for potential future development in the field of health care and diagnostics.