Bounded, efficient and multiply robust estimation of average treatment effects using instrumental variables

被引:95
作者
Wang, Linbo [1 ]
Tchetgen, Eric Tchetgen [1 ]
机构
[1] Harvard TH Chan Sch Publ Hlth, Boston, MA USA
基金
美国国家卫生研究院;
关键词
Binary outcome; Causal inference; Identification; Semiparametric inference; Unmeasured confounding; CAUSAL INFERENCE; RANDOMIZED-TRIALS; STRUCTURAL MODELS; MISSING DATA; OUTCOMES; IDENTIFICATION; NONCOMPLIANCE; REGRESSION; BIAS; IV;
D O I
10.1111/rssb.12262
中图分类号
O21 [概率论与数理统计]; C8 [统计学];
学科分类号
020208 ; 070103 ; 0714 ;
摘要
Instrumental variables are widely used for estimating causal effects in the presence of unmeasured confounding. Under the standard instrumental variable model, however, the average treatment effect is only partially identifiable. To address this, we propose novel assumptions that enable identification of the average treatment effect. Our identification assumptions are clearly separated from model assumptions that are needed for estimation, so researchers are not required to commit to a specific observed data model in establishing identification. We then construct multiple estimators that are consistent under three different observed data models, and multiply robust estimators that are consistent in the union of these observed data models. We pay special attention to the case of binary outcomes, for which we obtain bounded estimators of the average treatment effect that are guaranteed to lie between -1 and 1. Our approaches are illustrated with simulations and a data analysis evaluating the causal effect of education on earnings.
引用
收藏
页码:531 / 550
页数:20
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