Metabolism of non-growing bacteria

被引：34

作者：

Lempp, Martin ^{[1
,2
]}

Lubrano, Paul ^{[1
,2
]}

Bange, Gert ^{[2
,3
]}

Link, Hannes ^{[1
,2
]}

机构：

[1] Max Planck Inst Terr Microbiol, D-35043 Marburg, Germany

[2] SYNMIKRO Res Ctr, D-35043 Marburg, Germany

[3] Philipps Univ Marburg, Dept Chem, Hans Meerwein Str 6, D-35032 Marburg, Germany

来源：

BIOLOGICAL CHEMISTRY | 2020年 / 401卷 / 12期

关键词：

antibiotics; industrial biotechnology; metabolism; non-growing bacteria; starvation; BACILLUS-SUBTILIS; STARVATION; STRESS; GROWTH; ACID; FLUX;

D O I：

10.1515/hsz-2020-0201

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A main function of bacterial metabolism is to supply biomass building blocks and energy for growth. This seems to imply that metabolism is idle in non-growing bacteria. But how relevant is metabolism for the physiology of non-growing bacteria and how active is their metabolism? Here, we reviewed literature describing metabolism of non-growing bacteria in their natural environment, as well as in biotechnological and medical applications. We found that metabolism does play an important role during dormancy and that especially the demand for ATP determines metabolic activity of nongrowing bacteria.

引用

页码：1479 / 1485

页数：7

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