Severe idiopathic pulmonary fibrosis: A clinical approach

被引：3

作者：

Lipsi, R. ^{[1
]}

Mazzola, D. ^{[1
]}

Caminati, A. ^{[1
]}

Elia, D. ^{[1
]}

Lonati, C. ^{[2
]}

Harari, S. ^{[1
,2
]}

机构：

[1] IRCCS, Osped San Giuseppe MultiMed, Serv Fisiopatol Resp & Emodinam Polmonare, UO Pneumol & Terapia Semiintens Resp, Via San Vittore 12, I-20123 Milan, Italy

[2] Osped San Giuseppe MultiMed IRCCS, UO Med Gen, Via San Vittore 12, I-20123 Milan, Italy

来源：

EUROPEAN JOURNAL OF INTERNAL MEDICINE | 2018年 / 50卷

关键词：

Acute exacerbation of IPF; Lung transplantation; Palliation; Pirfenidone; Nintedanib; Lung cancer; INTERSTITIAL LUNG-DISEASE; ACUTE EXACERBATION; PALLIATIVE CARE; RISK-FACTORS; PIRFENIDONE; EFFICACY; TRANSPLANTATION; HYPERTENSION; VENTILATION; DEPRESSION;

D O I：

10.1016/j.ejim.2018.01.014

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Idiopathic pulmonary fibrosis (IPF) is a devastating progressive disease associated with a high mortality rate. Novel antifibrotic therapies have been recently demonstrated to slow disease progression and improve survival. However, the management of IPF remains a difficult challenge, since lung complications can still occur, particularly in patients with advanced-stage disease. This paper highlights the most common complications and difficult tasks related to severe IPF such as acute exacerbation of the disease, development of lung cancer, rapid disease progression, and indication for lung transplantation.

引用

页码：20 / 27

页数：8

共 54 条

[11] Acute Exacerbation of Idiopathic Pulmonary Fibrosis An International Working Group Report [J].

Collard, Harold R. ;

Ryerson, Christopher J. ;

Corte, Tamera J. ;

Jenkins, Gisli ;

Kondoh, Yasuhiro ;

Lederer, David J. ;

Lee, Joyce S. ;

Maher, Toby M. ;

Wells, Athol U. ;

Antoniou, Katerina M. ;

Behr, Juergen ;

Brown, Kevin K. ;

Cottin, Vincent ;

Flaherty, Kevin R. ;

Fukuoka, Junya ;

Hansell, David M. ;

Johkoh, Takeshi ;

Kaminski, Naftali ;

Kim, Dong Soon ;

Kolb, Martin ;

Lynch, David A. ;

Myers, Jeffrey L. ;

Raghu, Ganesh ;

Richeldi, Luca ;

Taniguchi, Hiroyuki ;

Martinez, Fernando J. .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2016, 194 (03) :265-275

[12] Quality of life of idiopathic pulmonary fibrosis patients [J].

De Vries, J ;

Kessels, BLJ ;

Drent, M .

EUROPEAN RESPIRATORY JOURNAL, 2001, 17 (05) :954-961

[13] Pulmonary rehabilitation for interstitial lung disease [J].

Dowman, Leona ;

Hill, Catherine J. ;

Holland, Anne E. .

COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2014, (10)

[14] The evidence of benefits of exercise training in interstitial lung disease: a randomised controlled trial [J].

Dowman, Leona M. ;

McDonald, Christine F. ;

Hill, Catherine J. ;

Lee, Annemarie L. ;

Barker, Kathryn ;

Boote, Claire ;

Glaspole, Ian ;

Goh, Nicole S. L. ;

Southcott, Anne M. ;

Burge, Angela T. ;

Gillies, Rebecca ;

Martin, Alicia ;

Holland, Anne E. .

THORAX, 2017, 72 (07) :610-619

[15] Apoptosis in lung injury and fibrosis [J].

Drakopanagiotakis, F. ;

Xifteri, A. ;

Polychronopoulos, V. ;

Bouros, D. .

EUROPEAN RESPIRATORY JOURNAL, 2008, 32 (06) :1631-1638

[16] Development of the new lung allocation system in the United States [J].

Egan, TM ;

Murray, S ;

Bustami, RT ;

Shearon, TH ;

McCullough, KR ;

Edwards, LB ;

Coke, MA ;

Garrity, ER ;

Sweet, SC ;

Heiney, DA ;

Grover, FL .

AMERICAN JOURNAL OF TRANSPLANTATION, 2006, 6 (05) :1212-1227

[17] Exacerbations in Idiopathic Pulmonary Fibrosis Triggered by Pulmonary and Nonpulmonary Surgery: A Case Series and Comprehensive Review of the Literature [J].

Ghatol, Abhijeet ;

Ruhl, A. Parker ;

Danoff, Sonye K. .

LUNG, 2012, 190 (04) :373-380

[18] Efficacy of pirfenidone for idiopathic pulmonary fibrosis: An Italian real life study [J].

Harari, S. ;

Caminati, A. ;

Albera, C. ;

Vancheri, C. ;

Poletti, V. ;

Pesci, A. ;

Luppi, F. ;

Saltini, C. ;

Agostini, C. ;

Bargagli, E. ;

Sebastiani, A. ;

Sanduzzi, A. ;

Giunta, V. ;

Della Porta, R. ;

Bandelli, G. P. ;

Puglisi, S. ;

Tomassetti, S. ;

Biffi, A. ;

Cerri, S. ;

Mari, A. ;

Cinetto, F. ;

Tirelli, F. ;

Farinelli, G. ;

Bocchino, M. ;

Specchia, C. ;

Confalonieri, M. .

RESPIRATORY MEDICINE, 2015, 109 (07) :904-913

[19] Toward better management of rare and orphan pulmonary diseases [J].

Harari, Sergio ;

Humbert, Marc .

EUROPEAN RESPIRATORY JOURNAL, 2016, 47 (05) :1334-1335

[20] Epidemiology of Idiopathic Pulmonary Fibrosis in Northern Italy [J].

Harari, Sergio ;

Madotto, Fabiana ;

Caminati, Antonella ;

Conti, Sara ;

Cesana, Giancarlo .

PLOS ONE, 2016, 11 (02)

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