Severe idiopathic pulmonary fibrosis: A clinical approach

被引:3
作者
Lipsi, R. [1 ]
Mazzola, D. [1 ]
Caminati, A. [1 ]
Elia, D. [1 ]
Lonati, C. [2 ]
Harari, S. [1 ,2 ]
机构
[1] IRCCS, Osped San Giuseppe MultiMed, Serv Fisiopatol Resp & Emodinam Polmonare, UO Pneumol & Terapia Semiintens Resp, Via San Vittore 12, I-20123 Milan, Italy
[2] Osped San Giuseppe MultiMed IRCCS, UO Med Gen, Via San Vittore 12, I-20123 Milan, Italy
关键词
Acute exacerbation of IPF; Lung transplantation; Palliation; Pirfenidone; Nintedanib; Lung cancer; INTERSTITIAL LUNG-DISEASE; ACUTE EXACERBATION; PALLIATIVE CARE; RISK-FACTORS; PIRFENIDONE; EFFICACY; TRANSPLANTATION; HYPERTENSION; VENTILATION; DEPRESSION;
D O I
10.1016/j.ejim.2018.01.014
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Idiopathic pulmonary fibrosis (IPF) is a devastating progressive disease associated with a high mortality rate. Novel antifibrotic therapies have been recently demonstrated to slow disease progression and improve survival. However, the management of IPF remains a difficult challenge, since lung complications can still occur, particularly in patients with advanced-stage disease. This paper highlights the most common complications and difficult tasks related to severe IPF such as acute exacerbation of the disease, development of lung cancer, rapid disease progression, and indication for lung transplantation.
引用
收藏
页码:20 / 27
页数:8
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