Effect of black and red cabbage on plasma carotenoid levels, lipid profile and oxidized low density lipoprotein

被引:14
作者
Bacchetti, Tiziana [1 ]
Tullii, Domenico [2 ]
Masciangelo, Simona [1 ]
Gesuita, Rosaria [3 ]
Skrami, Edlira [3 ]
Bruge, Francesca [4 ]
Silvestri, Sonia [4 ]
Orlando, Patrick [4 ]
Tiano, Luca [4 ]
Ferretti, Gianna [4 ]
机构
[1] Univ Politecn Marche, Dipartimento Sci Vita & Ambiente, I-60100 Ancona, Italy
[2] Italsur Srl, Notaresco, TE, Italy
[3] Univ Politecn Marche, Ctr Interdipartimentale Epidemiol Biostat & Infor, I-60100 Ancona, Italy
[4] Univ Politecn Marche, Dipartimento Sci Clin Specialist & Odontostomatol, I-60100 Ancona, Italy
关键词
Functional foods; Oxidized-LDL; Plasma lipids; Carotenoids; Antioxidants; Cabbage; VAR. ACEPHALA DC; BETA-CAROTENE; ANTIOXIDANT CAPACITY; BIOACTIVE COMPOUNDS; SPROUT EXTRACT; VITAMIN-C; IN-VITRO; HIGH-FAT; CHOLESTEROL; LDL;
D O I
10.1016/j.jff.2014.02.020
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
The bioavailability of carotenoids and the protective effect exerted by Brassica vegetables against lipoprotein peroxidation has not previously been investigated in humans. The aim of this study was to evaluate the bioavailability of carotenoids in black (Brassica oleracea L. var. acephala subvar. Laciniata L) and red cabbage (Brassica oleracea L. var. capitata L.f. rubra) and their protective effect against LDL oxidation. Moreover, we studied the effect on plasma lipid profile. Thirty-eight healthy volunteers (23 females and 15 males) participated in the 2-week intervention study which included a daily portion (300 g) of black and red cabbage. Plasma lutein and beta-carotene levels and total antioxidant capacity after dietary intervention were significantly increased. The results obtained demonstrated that Brassica supplementation favourably influenced serum lipid profile with a significant decrease in total cholesterol, LDL-cholesterol and oxidized LDL. Moreover, our results strengthen the hypothesis that the effect of dietary intervention could be modulated by baseline conditions of the subjects. (C) 2014 Elsevier Ltd. All rights reserved.
引用
收藏
页码:128 / 137
页数:10
相关论文
共 62 条
[11]   Dietary (Poly)phenolics in Human Health: Structures, Bioavailability, and Evidence of Protective Effects Against Chronic Diseases [J].
Del Rio, Daniele ;
Rodriguez-Mateos, Ana ;
Spencer, Jeremy P. E. ;
Tognolini, Massimiliano ;
Borges, Gina ;
Crozier, Alan .
ANTIOXIDANTS & REDOX SIGNALING, 2013, 18 (14) :1818-1892
[12]   The Relationship Between Reduction in Low-Density Lipoprotein Cholesterol by Statins and Reduction in Risk of Cardiovascular Outcomes: An Updated Meta-Analysis [J].
Delahoy, Philippa J. ;
Magliano, Dianna J. ;
Webb, Kate ;
Grobler, Mendel ;
Liew, Danny .
CLINICAL THERAPEUTICS, 2009, 31 (02) :236-244
[13]   Mechanisms of disease - Antioxidants and atherosclerotic heart disease [J].
Diaz, MN ;
Frei, B ;
Vita, JA ;
Keaney, JF .
NEW ENGLAND JOURNAL OF MEDICINE, 1997, 337 (06) :408-416
[14]   Identification, quantification and comparison of the principal bioactive compounds and external quality parameters of two broccoli cultivars [J].
Fernandez-Leon, M. F. ;
Fernandez-Leon, A. M. ;
Lozano, M. ;
Ayuso, M. C. ;
Gonzalez-Gomez, D. .
JOURNAL OF FUNCTIONAL FOODS, 2012, 4 (02) :465-473
[15]   Antioxidant capacity of plasma after red wine intake in human volunteers [J].
Fernández-Pachón, MS ;
Villaño, D ;
Troncoso, AM ;
García-Parrilla, MC .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2005, 53 (12) :5024-5029
[16]  
Frei B, 1996, VITAM HORM, V52, P1, DOI 10.1016/S0083-6729(08)60405-7
[17]   Adherence to a Mediterranean diet and plasma concentrations of lipid peroxidation in premenopausal women [J].
Gaskins, Audrey J. ;
Rovner, Alisha J. ;
Mumford, Sunni L. ;
Yeung, Edwina ;
Browne, Richard W. ;
Trevisan, Maurizio ;
Perkins, Neil J. ;
Wactawski-Wende, Jean ;
Schisterman, Enrique S. .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 2010, 92 (06) :1461-1467
[18]   SUPPLEMENTATION WITH BETA-CAROTENE IN-VIVO AND IN-VITRO DOES NOT INHIBIT LOW-DENSITY-LIPOPROTEIN OXIDATION [J].
GAZIANO, JM ;
HATTA, A ;
FLYNN, M ;
JOHNSON, EJ ;
KRINSKY, NI ;
RIDKER, PM ;
HENNEKENS, CH ;
FREI, B .
ATHEROSCLEROSIS, 1995, 112 (02) :187-195
[19]  
Gebhardt R, 2003, PLANTA MED, V69, P1071, DOI 10.1055/s-2003-45184
[20]  
Haegele AD, 2000, CANCER EPIDEM BIOMAR, V9, P421