Palladium-Catalyzed Direct C-H Arylation of Arenes Promoted by Quaternary Ammonium Salt

被引：5

作者：

Yang, Sabyuk ^{[2
]}

Hong, Soon Hyeok ^{[1
]}

机构：

[1] Korea Adv Inst Sci & Technol KAIST, Dept Chem, Daejeon 34141, South Korea

[2] Seoul Natl Univ, Dept Chem, Coll Nat Sci, Seoul 08826, South Korea

来源：

ASIAN JOURNAL OF ORGANIC CHEMISTRY | 2020年 / 9卷 / 11期

基金：

新加坡国家研究基金会;

关键词：

ammonium salt; arenes; C-H arylation; C-H functionalization center dot palladium; BOND FUNCTIONALIZATIONS; HETEROGENEOUS CATALYSIS; UNACTIVATED ARENES; COUPLING REACTIONS; HECK; COMPLEXES; RHODIUM; PD; HETEROARENES; MECHANISM;

D O I：

10.1002/ajoc.202000443

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new Pd-based catalytic system for the direct C-H arylation of arenes was developed. The use of a substoichiometric amount of quaternary ammonium salt as an additive with a Pd source achieved the direct arylation of unactivated arenes under milder reaction conditions in moderate to high yields. The ammonium salt generates the anionic palladium complex, thereby facilitating arylation by a concerted metalation-deprotonation process.

引用

页码：1846 / 1851

页数：6

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