Palladium-Catalyzed Direct C-H Arylation of Arenes Promoted by Quaternary Ammonium Salt

被引：5
作者：
Yang, Sabyuk [2 ]
Hong, Soon Hyeok [1 ]
机构：
[1] Korea Adv Inst Sci & Technol KAIST, Dept Chem, Daejeon 34141, South Korea
[2] Seoul Natl Univ, Dept Chem, Coll Nat Sci, Seoul 08826, South Korea
来源：
ASIAN JOURNAL OF ORGANIC CHEMISTRY | 2020年 / 9卷 / 11期
基金：
新加坡国家研究基金会;
关键词：
ammonium salt; arenes; C-H arylation; C-H functionalization center dot palladium; BOND FUNCTIONALIZATIONS; HETEROGENEOUS CATALYSIS; UNACTIVATED ARENES; COUPLING REACTIONS; HECK; COMPLEXES; RHODIUM; PD; HETEROARENES; MECHANISM;
D O I：
10.1002/ajoc.202000443
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A new Pd-based catalytic system for the direct C-H arylation of arenes was developed. The use of a substoichiometric amount of quaternary ammonium salt as an additive with a Pd source achieved the direct arylation of unactivated arenes under milder reaction conditions in moderate to high yields. The ammonium salt generates the anionic palladium complex, thereby facilitating arylation by a concerted metalation-deprotonation process.
引用
收藏
页码：1846 / 1851
页数：6
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