Ovarian cancer in female-to-male transsexuals: Report of two cases

被引：68

作者：

Hage, JJ

Dekker, JJML

Karim, RB

Verheijen, RHM

Bloemena, E

机构：

[1] Vrije Univ Amsterdam, Acad Ziekenhuis, Dept Plast & Reconstruct Surg, NL-1007 MB Amsterdam, Netherlands

[2] Vrije Univ Amsterdam, Acad Ziekenhuis, Dept Obstet & Gynaecol, NL-1007 MB Amsterdam, Netherlands

[3] Vrije Univ Amsterdam, Acad Ziekenhuis, Dept Pathol, NL-1007 MB Amsterdam, Netherlands

来源：

GYNECOLOGIC ONCOLOGY | 2000年 / 76卷 / 03期

关键词：

ovarian cancer; transsexualism; androgens; polycystic ovaries; growth factors;

D O I：

10.1006/gyno.1999.5720

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Background. Ovarium cancer is the fifth most common cause of cancer-related death in women and is the most common fatal gynecologic malignancy. So far, ovarium carcinoma has not been reported to have occurred in female-to-male transsexuals. Objective and method. We report on two such cases. Long-term exposure to increased levels of endogenous and exogenous androgens is hypothesized to constitute an additional risk factor in transsexuals as it has been associated with ovarian epithelian cancer. Conclusion. Simultaneous salpingo-oophorectomy should be performed in any female-to-male transsexual undergoing hysterectomy in the course of gender-confirming therapy. (C) 2000 Academic Press.

引用

收藏

页码：413 / 415

页数：3

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