Emerging Roles of RNA Modification: m6A and U-Tail

被引：260

作者：

Lee, Mihye ^{[1
,2
]}

Kim, Boseon ^{[1
,2
]}

Kim, V. Narry ^{[1
,2
]}

机构：

[1] Inst for Basic Sci Korea, IBS Ctr RNA Res, Seoul 151742, South Korea

[2] Seoul Natl Univ, Sch Biol Sci, Seoul 151742, South Korea

来源：

CELL | 2014年 / 158卷 / 05期

关键词：

ARABIDOPSIS MESSENGER-RNA; 3' END; MICRORNA BIOGENESIS; POLY(A) POLYMERASE; PRE-MICRORNA; NUCLEAR-RNA; 5' TERMINUS; STEM-LOOP; METHYLATION; URIDYLATION;

D O I：

10.1016/j.cell.2014.08.005

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Although more than 100 types of RNA modification have been described thus far, most of them were thought to be rare in mRNAs and in regulatory noncoding RNAs. Recent developments have unveiled that at least some of the modifications are considerably abundant and widely conserved. This Minireview summarizes the molecular machineries and biological functions of methylation (N6-methyladenosine, m(6)A) and uridylation (U-tail).

引用

页码：980 / 987

页数：8

共 50 条

[21] The detection and functions of RNA modification m6A based on m6A writers and erasers
Zhang, Wei
Qian, Yang
Jia, Guifang
JOURNAL OF BIOLOGICAL CHEMISTRY, 2021, 297 (02)
[22] Roles of m6A modification in oral cancer (Review)
Liu, Huimin
Wang, Yinyu
Xue, Tianyi
Yang, Zhijing
Kan, Shaoning
Hao, Ming
Gao, Yang
Wang, Dongxu
Liu, Weiwei
INTERNATIONAL JOURNAL OF ONCOLOGY, 2023, 62 (01)
[23] The Emerging Role of m6A Modification in Endocrine Cancer
Ji, Xiaoyu
Wang, Zhiyuan
Sun, Wei
Zhang, Hao
CANCERS, 2023, 15 (04)
[24] The functional roles of m6A modification in prostate cancer
Zhang, Fa
Chen, Feng
Wang, Chao
Zhou, Feng-Hai
PROTEOMICS CLINICAL APPLICATIONS, 2023, 17 (06)
[25] N6-Adenosine Methylation (m6A) RNA Modification: an Emerging Role in Cardiovascular Diseases
Chen, Ye-shi
Ouyang, Xin-ping
Yu, Xiao-hua
Novak, Petr
Zhou, Le
He, Ping-ping
Yin, Kai
JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH, 2021, 14 (05) : 857 - 872
[26] N6-methyladenosine (m6A) RNA modification in tumor immunity
Zheng, Siyi
Han, Hui
Lin, Shuibin
CANCER BIOLOGY & MEDICINE, 2022, 19 (04) : 385 - 397
[27] The Emerging Clinical Application of m6A RNA Modification in Inflammatory Bowel Disease and Its Associated Colorectal Cancer
Xu, Xinwei
Huang, Jintu
Ocansey, Dickson Kofi Wiredu
Xia, Yuxuan
Zhao, Zihan
Xu, Zhiwei
Yan, Yongmin
Zhang, Xu
Mao, Fei
JOURNAL OF INFLAMMATION RESEARCH, 2021, 14 : 3289 - 3306
[28] RNA m6A modification, signals for degradation or stabilisation?
Wei, Guifeng
BIOCHEMICAL SOCIETY TRANSACTIONS, 2024, 52 (02) : 707 - 717
[29] Targeting the RNA m6A modification for cancer immunotherapy
Li, Xinxin
Ma, Shoubao
Deng, Youcai
Yi, Ping
Yu, Jianhua
MOLECULAR CANCER, 2022, 21 (01)
[30] Advances in the role of m6A RNA modification in cancer metabolic reprogramming
Han, Xiu
Wang, Lin
Han, Qingzhen
CELL AND BIOSCIENCE, 2020, 10 (01)

← 1 2 3 4 5 →