Emerging Roles of RNA Modification: m6A and U-Tail

被引：262

作者：

Lee, Mihye ^{[1
,2
]}

Kim, Boseon ^{[1
,2
]}

Kim, V. Narry ^{[1
,2
]}

机构：

[1] Inst for Basic Sci Korea, IBS Ctr RNA Res, Seoul 151742, South Korea

[2] Seoul Natl Univ, Sch Biol Sci, Seoul 151742, South Korea

来源：

CELL | 2014年 / 158卷 / 05期

关键词：

ARABIDOPSIS MESSENGER-RNA; 3' END; MICRORNA BIOGENESIS; POLY(A) POLYMERASE; PRE-MICRORNA; NUCLEAR-RNA; 5' TERMINUS; STEM-LOOP; METHYLATION; URIDYLATION;

D O I：

10.1016/j.cell.2014.08.005

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Although more than 100 types of RNA modification have been described thus far, most of them were thought to be rare in mRNAs and in regulatory noncoding RNAs. Recent developments have unveiled that at least some of the modifications are considerably abundant and widely conserved. This Minireview summarizes the molecular machineries and biological functions of methylation (N6-methyladenosine, m(6)A) and uridylation (U-tail).

引用

页码：980 / 987

页数：8

共 50 条

[1] Emerging roles of m6A RNA modification in cancer therapeutic resistance
Wei-Wei Liu
Zhong-Yuan Zhang
Fei Wang
Hao Wang
Experimental Hematology & Oncology, 12
[2] Emerging roles of m6A RNA modification in cancer therapeutic resistance
Liu, Wei-Wei
Zhang, Zhong-Yuan
Wang, Fei
Wang, Hao
EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2023, 12 (01)
[3] The emerging roles of m6A modification in liver carcinogenesis
Pan, Xue-yin
Huang, Cheng
Li, Jun
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2021, 17 (01): : 271 - 284
[4] The roles and implications of RNA m6A modification in cancer
Deng, Xiaolan
Qing, Ying
Horne, David
Huang, Huilin
Chen, Jianjun
NATURE REVIEWS CLINICAL ONCOLOGY, 2023, 20 (08) : 507 - 526
[5] The roles and implications of RNA m6A modification in cancer
Xiaolan Deng
Ying Qing
David Horne
Huilin Huang
Jianjun Chen
Nature Reviews Clinical Oncology, 2023, 20 : 507 - 526
[6] Crosstalk Between Histone and m6A Modifications and Emerging Roles of m6A RNA Methylation
Xu, Zibin
Xie, Tingfei
Sui, Xiaolu
Xu, Yunpeng
Ji, Lecai
Zhang, Yanzi
Zhang, Aisha
Chen, Jihong
FRONTIERS IN GENETICS, 2022, 13
[7] m6A modification in RNA: biogenesis, functions and roles in gliomas
Zhang, Yuhao
Geng, Xiuchao
Li, Qiang
Xu, Jianglong
Tan, Yanli
Xiao, Menglin
Song, Jia
Liu, Fulin
Fang, Chuan
Wang, Hong
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2020, 39 (01)
[8] Emerging role of RNA m6A modification in aging regulation
Zeming Wu
Si Wang
Juan Carlos Izpisua Belmonte
Weiqi Zhang
Jing Qu
Guang-Hui Liu
Current Medicine, 1 (1):
[9] m6A modification in RNA: biogenesis, functions and roles in gliomas
Yuhao Zhang
Xiuchao Geng
Qiang Li
Jianglong Xu
Yanli Tan
Menglin Xiao
Jia Song
Fulin Liu
Chuan Fang
Hong Wang
Journal of Experimental & Clinical Cancer Research, 39
[10] Emerging role of RNA m6A modification in chronic pain
Albik, Sfian
Tao, Yuan-Xiang
PAIN, 2021, 162 (07) : 1897 - 1898

← 1 2 3 4 5 →