Ocular promoting activity of grape polyphenols-A review

被引：19
作者：
Natarajan, Sithranga Boopathy [1 ]
Hwang, Jin-Woo [1 ,2 ]
Kim, Yon-Suk [1 ,2 ]
Kim, Eun-Kyung [1 ,2 ]
Park, Pyo-Jam [1 ,2 ]
机构：
[1] Konkuk Univ, Dept Biotechnol, Chungju 380701, South Korea
[2] Konkuk Univ, Nokyong Res Ctr, Chungju 380701, South Korea
来源：
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY | 2017年 / 50卷
关键词：
Ocular promotion; Grape polyphenols; Eye disease; Diabetes; Hypertension; VITIS-VINIFERA L; OXIDATIVE STRESS; RED WINE; SEED EXTRACT; ENDOTHELIAL DYSFUNCTION; INSULIN-SECRETION; RICH EXTRACTS; ANTHOCYANINS; INFLAMMATION; PREVENTION;
D O I：
10.1016/j.etap.2016.12.004
中图分类号：
X [环境科学、安全科学];
学科分类号：
08 ; 0830 ;
摘要：
The eye is a sensitive organ with complex optical system involves in the perception of light. Although it has several protective mechanisms by itself, various physiological and metabolic disorders are detrimental to the proper functioning of the visual system. Grape juice has long been used worldwide for its potent medicinal values including ocular promotion. Bioactivities of grape products are highly attributed to the presence of health promoting phytochemicals in them. Some phytochemicals present in the grape juice have been involved in the maintenance of intra-ocular pressure, regulation of glucose metabolisms and suppression of pro-inflammatory cytokines in the system. Particularly, the grape derived phytochemicals involve in minimizing various eye defects such as macular degradation, uvea, cataract formation, red eye, diabetic retinopathy and so on. However, only limited number of studies has been conducted so far focusing the ocular promoting activity of grape polyphenols. In this review, we discuss the role of grape polyphenols in ocular promotion relating their anti-oxidant, anti-microbial, anti-aging, anti-hypertensive and anti-inflammatory properties. (C) 2016 Published by Elsevier B.V.
引用
收藏
页码：83 / 90
页数：8
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