Polycationic liposome-mediated extracellular superoxide dismutase gene delivery leads to high levels of the transgene expression and prevents acute liver injury in mice

被引:0
|
作者
Wu, J
Liu, L
Yen, RD
Catana, A
Zern, MA
Nantz, MH
Marklund, SL
机构
[1] Univ Calif Davis, Med Ctr, Dept Internal Med, Transplant Res Program, Sacramento, CA 95817 USA
[2] Univ Calif Davis, Dept Chem, Davis, CA 95616 USA
[3] Umea Univ, Dept Med Sci, Sect Clin Chem, Umea, Sweden
关键词
D O I
暂无
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
677
引用
收藏
页码:S256 / S256
页数:1
相关论文
共 11 条
  • [1] Polycationic liposome-mediated extracellular superoxide dismutase gene delivery prevents acute liver injury in mice.
    Wu, J
    Liu, L
    Yen, R
    Le, HT
    Zern, MA
    Nantz, MH
    Marklund, SL
    HEPATOLOGY, 2003, 38 (04) : 240A - 241A
  • [2] Liposome-mediated extracellular superoxide dismutase gene delivery protects against acute liver injury in mice
    Wu, J
    Liu, L
    Yen, RD
    Catana, A
    Nantz, MH
    Zern, MA
    HEPATOLOGY, 2004, 40 (01) : 195 - 204
  • [4] LIPOSOME-MEDIATED AUGMENTATION OF SUPEROXIDE-DISMUTASE IN ENDOTHELIAL-CELLS PREVENTS OXYGEN INJURY
    FREEMAN, BA
    YOUNG, SL
    CRAPO, JD
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1983, 258 (20) : 2534 - 2542
  • [5] Liposome-mediated extracellular superoxide dismutase gene delivery protects against reactive oxygen species-associated hepatocellular injury in vitro and in vivo
    Wu, J
    Liu, L
    Zern, MA
    Nantz, MH
    Marklund, SL
    MOLECULAR THERAPY, 2003, 7 (05) : S169 - S169
  • [6] Cationic liposome-mediated gene delivery to the liver and to hepatocellular carcinomas in mice
    Mohr, L
    Yoon, SK
    Eastman, SJ
    Chu, Q
    Scheule, RK
    Scaglioni, PP
    Geissler, M
    Heintges, T
    Blum, HE
    Wands, JR
    HUMAN GENE THERAPY, 2001, 12 (07) : 799 - 809
  • [7] Viral gene delivery of superoxide dismutase prevents experimental cholestasis-induced liver injury in the rat.
    Zhong, Z
    Froh, M
    Wheeler, MD
    Thurman, RG
    HEPATOLOGY, 2000, 32 (04) : 180A - 180A
  • [8] Viral gene delivery of extracellular superoxide dismutase reduces early alcohol-induced liver injury in the mouse.
    Gaebele, E
    Arteel, GE
    Wheeler, M
    Uesugi, T
    Thurman, RG
    HEPATOLOGY, 2001, 34 (04) : 467A - 467A
  • [9] Lentivirus-mediated superoxide dismutase1 gene delivery protects against oxidative stress-induced liver injury in mice
    Venugopal, Senthil Kumar
    Wu, Jian
    Catana, Andreea M.
    Eisenbud, Lauren
    He, Song-Qing
    Duan, Yu-You
    Follenzi, Antonia
    Zern, Mark A.
    LIVER INTERNATIONAL, 2007, 27 (10) : 1311 - 1322
  • [10] Direct Intra-Brain LV-Mediated Gene Delivery Leads to Widespread Transgene Distribution and High-Level Enzymatic Correction in the Whole CNS of Twitcher Mice
    Lattanzi, Annalisa
    Maderna, Claudio
    Amendola, Mario
    Sergi, Lucia Sergi
    Conti, Daniele
    Martino, Sabata
    Naldini, Luigi
    Gritti, Angela
    MOLECULAR THERAPY, 2009, 17 : S340 - S340