T cell antigen receptor signal transduction

被引：267
|
作者：
Qian, DP [1 ]
Weiss, A [1 ]
机构：
[1] UNIV CALIF SAN FRANCISCO,HOWARD HUGHES MED INST,DEPT IMMUNOL & MICROBIOL,SAN FRANCISCO,CA 94143
来源：
CURRENT OPINION IN CELL BIOLOGY | 1997年 / 9卷 / 02期
关键词：
D O I：
10.1016/S0955-0674(97)80064-6
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The T cell antigen receptor (TCR) initiates signal transduction by activating multiple cytoplasmic protein tyrosine kinases (PTKs). Considerable progress in the field of TCR signal transduction has been made in three areas recently: first, in understanding the structure and function of the PTK ZAP-70; second, in the elucidation of the function of the substrates and pathways downstream of the PTKs; and third, in the identification of molecules that negatively regulate TCR signalling.
引用
收藏
页码：205 / 212
页数：8
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