Genetically modified animal models as tools for studying bone and mineral metabolism

被引：26
|
作者：
Davey, RA
MacLean, HE
McManus, JF
Findlay, DM
Zajac, JD
机构：
[1] Univ Melbourne, Dept Med, Heidelberg, Vic 3084, Australia
[2] Univ Adelaide, Dept Orthopaed & Trauma, Hanson Inst, Adelaide, SA, Australia
来源：
JOURNAL OF BONE AND MINERAL RESEARCH | 2004年 / 19卷 / 06期
关键词：
animal models; gene knockout/in; osteoblasts; osteoclasts; chondrocytes;
D O I：
10.1359/JBMR.040206
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Genetic modification of mice is a powerful tool for the study of bone development and metabolism. This review discusses the advantages and disadvantages of various approaches used in bone-related research and the contributions these studies have made to bone biology.
引用
收藏
页码：882 / 892
页数：11
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