Physicochemical determinants of drug-like monoclonal antibodies

被引:0
|
作者
Zhang, Yulei [1 ]
Rabia, Lilia [2 ]
Ludwig, Seth [2 ]
Starr, Charles [1 ]
Gupta, Priyanka [2 ]
Julian, Mark [2 ]
Tessier, Peter [3 ]
机构
[1] Univ Michigan, Chem Engn, Ann Arbor, MI 48109 USA
[2] Rensselaer Polytech Inst, Ann Arbor, MI USA
[3] Rensselaer Polytech Inst, Chem & Biol Engn, Troy, NY USA
来源
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2019年 / 257卷
关键词
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
204
引用
收藏
页数:1
相关论文
共 50 条
  • [1] Physiochemical determinants of drug-like monoclonal antibodies
    Rabia, Lilia
    Ludwig, Seth
    Zhang, Yulei
    Julian, Mark
    Tessier, Peter
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2018, 255
  • [2] Physicochemical Rules for Identifying Monoclonal Antibodies with Drug-like Specificity
    Zhang, Yulei
    Wu, Lina
    Gupta, Priyanka
    Desai, Alec A.
    Smith, Matthew D.
    Rabia, Lilia A.
    Ludwig, Seth D.
    Tessier, Peter M.
    MOLECULAR PHARMACEUTICS, 2020, 17 (07) : 2555 - 2569
  • [3] Selecting and engineering monoclonal antibodies with drug-like specificity
    Starr, Charles G.
    Tessier, Peter M.
    CURRENT OPINION IN BIOTECHNOLOGY, 2019, 60 : 119 - 127
  • [4] Approaches to expand the conventional toolbox for discovery and selection of antibodies with drug-like physicochemical properties
    Svilenov, Hristo L.
    Arosio, Paolo
    Menzen, Tim
    Tessier, Peter
    Sormanni, Pietro
    MABS, 2023, 15 (01)
  • [5] Toward Drug-Like Multispecific Antibodies by Design
    Sawant, Manali S.
    Streu, Craig N.
    Wu, Lina
    Tessier, Peter M.
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 21 (20) : 1 - 41
  • [6] Chemoinformatics - predicting the physicochemical properties of 'drug-like' molecules
    Blake, JF
    CURRENT OPINION IN BIOTECHNOLOGY, 2000, 11 (01) : 104 - 107
  • [7] Physicochemical properties of drug-like fluids using thermodynamic models
    Akbari, Falamarz
    Farhadi, Mitra
    PHYSICS AND CHEMISTRY OF LIQUIDS, 2022, 60 (01) : 95 - 110
  • [8] The Impact of Physicochemical and Molecular Properties in Drug Design: Navigation in the "Drug-Like" Chemical Space
    Vallianatou, Theodosia
    Giaginis, Costas
    Tsantili-Kakoulidou, Anna
    GENEDIS 2014: NEURODEGENERATION, 2015, 822 : 187 - 194
  • [9] Drug-like index: A new approach to measure drug-like compounds and their diversity
    Xu, J
    Stevenson, J
    JOURNAL OF CHEMICAL INFORMATION AND COMPUTER SCIENCES, 2000, 40 (05): : 1177 - 1187
  • [10] Improving the odds in discriminating "Drug-like" from "Non Drug-like" compounds
    Frimurer, TM
    Bywater, R
    Nærum, L
    Lauritsen, LN
    Brunak, S
    JOURNAL OF CHEMICAL INFORMATION AND COMPUTER SCIENCES, 2000, 40 (06): : 1315 - 1324