Metal-free synthesis of activated ynesulfonamides and tertiary enesulfonamides

被引：7

作者：

Andna, Lucile ^{[1
]}

Miesch, Laurence ^{[1
]}

机构：

[1] CNRS UdS UMR 7177, Inst Chim, Equipe Synth Organ & Phytochim, 4 Rue Blaise Pascal CS 90032, F-67081 Strasbourg, France

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2019年 / 17卷 / 23期

关键词：

STEREOSELECTIVE-SYNTHESIS; NUCLEOPHILIC-ADDITION; ALKYNYL BROMIDES; YNAMIDES; SULFONAMIDES; ENAMIDES; SPIROCYCLIZATION; CYCLIZATION; AMIDATIONS; ALKENES;

D O I：

10.1039/c9ob00947g

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An operationally simple synthesis of activated ynesulfonamides and enesulfonamides is described. Ynesulfonamides can be obtained through reaction of sulfonylamides with activated bromoalkynes and Triton B in a short time at room temperature. Likewise, terminal alkynes react with sulfonylamides to provide enesulfonamides. Z/E enesulfonamides can be transformed exclusively into E enesulfonamides.

引用

页码：5688 / 5692

页数：5

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