Role of magnesium, coenzyme Q10 riboflavin, and vitamin B12 in migraine prophylaxis

被引：46

作者：

Bianchi, A ^{[1
]}

Salomone, S

Caraci, F

Pizza, V

Bernardini, R

D'Amato, CC

机构：

[1] Univ Salerno, Dept Pharmaceut Sci, I-84084 Fisciano, Italy

[2] Univ Catania, Dept Pharmaceut Sci, I-95125 Catania, Italy

[3] Univ Catania, Dept Expt & Clin Pharmacol, I-95125 Catania, Italy

[4] Univ Naples 2, Dept Neurol, I-80138 Naples, Italy

[5] S Luca Hosp, Neurophysiopathol Serv, I-84078 Salerno, Italy

来源：

VITAMINS AND HORMONES - ADVANCES IN RESEARCH AND APPLICATIONS, VOL 69 | 2004年 / 69卷

关键词：

D O I：

10.1016/S0083-6729(04)69011-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Migraine is a neurovascular syndrome characterized by recurrent headache associated with other symptoms, eventually preceded by aura. This chapter reviews the involvement of some mineral, coenzyme, and vitamin defects in the pathogenesis of migraine headaches and focuses on their potential therapeutic use in the preventive treatment for migraine. The therapeutic potential of magnesium, coenzyme Q(10), riboflavin, and vitamin B-12 can be cautiously inferred from some published open clinical trials; it should, however, be considered that double-blind randomized larger studies are needed to correctly estimate the impact of the placebo effect in these promising therapies. (C) 2004 Elsevier Inc.

引用

页码：297 / 312

页数：16

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