A review of the spectrum of clinical ocular fundus findings in P-falciparum malaria in African children with a proposed classification and grading system

被引：74

作者：

Lewallen, S

Harding, SP

Ajewole, J

Schulenburg, WE

Molyneux, ME

Marsh, K

Usen, S

White, NJ

Taylor, TE

机构：

[1] Univ British Columbia, St Pauls Hosp, Dept Ophthalmol, British Columbia Ctr Epidemiol & Int Ophthalmol, Vancouver, BC V6Z 1Y6, Canada

[2] Royal Liverpool Univ Hosp, St Pauls Eye Unit, Liverpool, Merseyside, England

[3] Natl Eye Care Project, Banjul, Gambia

[4] Western Eye Hosp, London, England

[5] Univ Malawi, Coll Med, Wellcome Trust Labs, Zomba, Malawi

[6] Univ Malawi, Coll Med, Malaria Project, Zomba, Malawi

[7] Univ Liverpool, Sch Trop Med, Liverpool L69 3BX, Merseyside, England

[8] Kenya Med Res Inst, Clin Res Ctr, Kilifi, Kenya

[9] MRC Labs, Banjul, Gambia

[10] Mahidol Univ, Fac Trop Med, Bangkok, Thailand

[11] Michigan State Univ, Coll Osteopath Med, E Lansing, MI 48824 USA

来源：

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE | 1999年 / 93卷 / 06期

基金：

英国惠康基金;

关键词：

malaria; Plasmodium-falciparum; ophthalmology; classification system; Malawi; Kenya; The Gambia;

D O I：

10.1016/S0035-9203(99)90071-8

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Ocular fundus pathology in Plasmodium falciparum malaria is common and has prognostic significance. We have made a collaborative effort to document the ocular features in several populations. Based on examination of 735 patients in Malawi, Kenya and The Gambia by direct and indirect ophthalmoscopy with dilated pupils, we have determined that the 5 distinct clinical features (in order of frequency) include retinal whitening, haemorrhages, unique Vessel abnormalities, papilloedema, and cotton wool spots. Photographs and descriptions of these are presented, along with a proposed grading scheme.

引用

页码：619 / 622

页数：4

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