Multisystem Inflammatory Syndrome Associated With Coronavirus Disease in Children A Multi-centered Study in Belem, Para, Brazil

被引:23
作者
de Farias, Emmerson C. F. [1 ,2 ]
Pedro Piva, Jefferson [3 ]
de Mello, Mary L. F. M. F. [1 ]
do Nascimento, Luciana M. P. P. [1 ]
Costa, Carina C. [1 ]
Machado, Mayara M. M. [1 ]
Rodrigues, Thatiane da S. [1 ]
Carvalho, Railana D. F. P. [1 ]
Alves, Marilia C. B. [1 ]
Aires, Larisse F. Q. [1 ]
Cotta, Marilia L. M. [4 ]
Pedreira, Ana R. G. [5 ]
Saraty, Salma B. [6 ]
Lima, Miriam C. [6 ]
Justino, Maria C. A. [3 ,7 ]
机构
[1] Fundacao Santa Casa de Misericordia Paras Hosp FS, Dept Pediat, Div Pediat Intens Care, Belem, Para Pa, Brazil
[2] Metropolitan Univ Ctr Amazon FAMAZ, Dept Child Hlth, Belem, Para Pa, Brazil
[3] Univ Fed Rio Grande Sul UFRGS, Dept Pediat, Div Pediat Intens Care, Porto Alegre, RS, Brazil
[4] Fundacao Hosp Clin Gaspar Vianas Hosp FHCGV, Dept Pediat, Div Pediat Intens Care, Belem, Para Pa, Brazil
[5] Proinfantils Hosp HPI, Dept Pediat, Div Pediat Intens Care, Belem, Para Pa, Brazil
[6] Pronto Socorro Municipal Mario Pinottis Hosp HPSM, Dept Pediat, Pediat Intens Care Div, Belem, Para Pa, Brazil
[7] Brazilian Minist Hlth IEC, Evandro Chagas Inst, Viirol Sect, Secretariat Hlth Surveillance, Ananindeua, Para Pa, Brazil
关键词
COVID-19; coronavirus; severe acute respiratory syndrome; multiple organ failure; multisystem inflammatory syndrome;
D O I
10.1097/INF.0000000000002865
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
We described the characteristics of 11 children with pediatric multisystem inflammatory syndrome-temporally associated with SARS-CoV-2. The main clinical indications for hospital admission were vasogenic toxic shock (n = 2), Kawasaki disease (n = 4), and Kawasaki disease shock syndrome (n = 5). The echocardiography findings were abnormal in 63% of cases. All patients had 2 or more organ dysfunctions, and the mortality rate was 18%.
引用
收藏
页码:E374 / E376
页数:3
相关论文
共 16 条
[1]  
[Anonymous], 2020, PEDIAT CARDIOL
[2]   Why and How Is Hyperferritinemic Sepsis Different From Sepsis Without Hyperferritinemia?* [J].
Carcillo, Joseph A. ;
Kernan, Kate K. ;
Horvat, Christopher M. ;
Simon, Dennis W. ;
Aneja, Rajesh K. .
PEDIATRIC CRITICAL CARE MEDICINE, 2020, 21 (05) :509-512
[3]   Multisystem Inflammatory Syndrome Related to COVID-19 in Previously Healthy Children and Adolescents in New York City [J].
Cheung, Eva W. ;
Zachariah, Philip ;
Gorelik, Mark ;
Boneparth, Alexis ;
Kernie, Steven G. ;
Orange, Jordan S. ;
Milner, Joshua D. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2020, 324 (03) :294-296
[4]   Internet addiction among adolescents in a western Brazilian Amazonian city [J].
Dalamaria, Tatiane ;
Pinto, Wagner de Jesus ;
Farias, Edson dos Santos ;
de Souza, Orivaldo Florencio .
REVISTA PAULISTA DE PEDIATRIA, 2021, 39
[5]   Epidemiology of COVID-19 Among Children in China [J].
Dong, Yuanyuan ;
Mo, Xi ;
Hu, Yabin ;
Qi, Xin ;
Jiang, Fan ;
Jiang, Zhongyi ;
Tong, Shilu .
PEDIATRICS, 2020, 145 (06)
[6]   Multisystem Inflammatory Syndrome in US Children and Adolescents [J].
Feldstein, Leora R. ;
Rose, Erica B. ;
Horwitz, Steven M. ;
Collins, Jennifer P. ;
Newhams, Margaret M. ;
Son, Mary Beth F. ;
Newburger, Jane W. ;
Kleinman, Lawrence C. ;
Heidemann, Sabrina M. ;
Martin, Amarilis A. ;
Singh, Aalok R. ;
Li, Simon ;
Tarquinio, Keiko M. ;
Jaggi, Preeti ;
Oster, Matthew E. ;
Zackai, Sheemon P. ;
Gillen, Jennifer ;
Ratner, Adam J. ;
Walsh, Rowan F. ;
Fitzgerald, Julie C. ;
Keenaghan, Michael A. ;
Alharash, Hussam ;
Doymaz, Sule ;
Clouser, Katharine N. ;
Giuliano, John S. ;
Gupta, Anjali ;
Parker, Robert M. ;
Maddux, Aline B. ;
Havalad, Vinod ;
Ramsingh, Stacy ;
Bukulmez, Hulya ;
Bradford, Tamara T. ;
Smith, Lincoln S. ;
Tenforde, Mark W. ;
Carroll, Christopher L. ;
Riggs, Becky J. ;
Gertz, Shira J. ;
Daube, Ariel ;
Lansell, Amanda ;
Coronado Munoz, Alvaro ;
Hobbs, Charlotte V. ;
Marohn, Kimberly L. ;
Halasa, Natasha B. ;
Patel, Manish M. ;
Randolph, Adrienne G. .
NEW ENGLAND JOURNAL OF MEDICINE, 2020, 383 (04) :334-346
[7]  
Feldstein LR., 2020, Multisystem inflammatory syndrome in children and adolescents temporally related to COVID-19, V383, P334
[8]   COVID-19 and Individual Genetic Susceptibility/Receptivity: Role of ACE1/ACE2 Genes, Immunity, Inflammation and Coagulation. Might the Double X-Chromosome in Females Be Protective against SARS-CoV-2 Compared to the Single X-Chromosome in Males? [J].
Gemmati, Donato ;
Bramanti, Barbara ;
Serino, Maria Luisa ;
Secchiero, Paola ;
Zauli, Giorgio ;
Tisato, Veronica .
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 21 (10)
[9]   Acute myocarditis and multisystem inflammatory emerging disease following SARS-CoV-2 infection in critically ill children [J].
Grimaud, Marion ;
Starck, Julie ;
Levy, Michael ;
Marais, Clemente ;
Chareyre, Judith ;
Khraiche, Diala ;
Leruez-Ville, Marianne ;
Quartier, Pierre ;
Leger, Pierre Louis ;
Geslain, Guillaume ;
Semaan, Nada ;
Moulin, Florence ;
Bendavid, Matthieu ;
Jean, Sandrine ;
Poncelet, Geraldine ;
Renolleau, Sylvain ;
Oualha, Mehdi .
ANNALS OF INTENSIVE CARE, 2020, 10 (01)
[10]  
Kuri-Cervantes Leticia, 2020, bioRxiv, DOI 10.1101/2020.05.18.101717