Potential Health Benefits of Olive Oil and Plant Polyphenols

被引:465
作者
Gorzynik-Debicka, Monika [1 ]
Przychodzen, Paulina [1 ]
Cappello, Francesco [2 ,3 ]
Kuban-Jankowska, Alicja [1 ]
Gammazza, Antonella Marino [2 ,3 ]
Knap, Narcyz [1 ]
Wozniak, Michal [1 ]
Gorska-Ponikowska, Magdalena [1 ,4 ]
机构
[1] Med Univ Gdansk, Dept Med Chem, PL-80211 Gdansk, Poland
[2] Univ Palermo, Dept Expt Biomed & Clin Neurosci BioNeC, I-90127 Palermo, Italy
[3] Euromediterranean Inst Sci & Technol IEMEST, I-90136 Palermo, Italy
[4] Univ Stuttgart, Dept Biophys, Inst Biomat & Biomol Syst, D-70569 Stuttgart, Germany
关键词
olive oil; Olea europea; polyphenols; oleuropein; hydroxytyrosol; anticancer therapy; PHENOLIC-COMPOUNDS; ANTIOXIDANT ACTIVITY; MEDITERRANEAN DIET; OXIDATIVE STRESS; LEAF EXTRACT; VOLATILE COMPOUNDS; IN-VITRO; OLEUROPEIN; CANCER; CELLS;
D O I
10.3390/ijms19030686
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Beneficial effects of natural plant polyphenols on the human body have been evaluated in a number of scientific research projects. Bioactive polyphenols are natural compounds of various chemical structures. Their sources are mostly fruits, vegetables, nuts and seeds, roots, bark, leaves of different plants, herbs, whole grain products, processed foods (dark chocolate), as well as tea, coffee, and red wine. Polyphenols are believed to reduce morbidity and/or slow down the development of cardiovascular and neurodegenerative diseases as well as cancer. Biological activity of polyphenols is strongly related to their antioxidant properties. They tend to reduce the pool of reactive oxygen species as well as to neutralize potentially carcinogenic metabolites. A broad spectrum of health-promoting properties of plant polyphenols comprises antioxidant, anti-inflammatory, anti-allergic, anti-atherogenic, anti-thrombotic, and anti-mutagenic effects. Scientific studies present the ability of polyphenols to modulate the human immune system by affecting the proliferation of white blood cells, and also the production of cytokines or other factors that participate in the immunological defense. The aim of the review is to focus on polyphenols of olive oil in context of their biological activities.
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页数:13
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