Relevance of commercial diagnostic tests to detection of enteric adenovirus infections in South Africa

被引：19
作者：
Moore, PL
Steele, AD
Alexander, JJ
机构：
[1] Univ Witwatersrand, Dept Microbiol, Johannesburg, South Africa
[2] Med Univ S Africa, Dept Virol, MRC, Medunsa Diarrhoeal Pathogens Res Unit, Pretoria, South Africa
来源：
JOURNAL OF CLINICAL MICROBIOLOGY | 2000年 / 38卷 / 04期
关键词：
D O I：
10.1128/JCM.38.4.1661-1663.2000
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The prevalence of enteric adenoviruses detected by an in-house enzyme-linked immunosorbent assay (the RIVM-ELISA) ranged from 13 to 38%, and subgroup F adenoviruses comprised 86%. All subgroup F adenoviruses reacted with both RIVM anti-adenovirus type 40 (Ad40) and anti-adenovirus type 41 (Ad41) monoclonal antibodies but were not detected by Adenoclone Type 40/41 enzyme immunoassay (EU). The correlation between the Biotrin EW and RIVM-ELISA results was low (26%). Immunospecific tests suggest that a significant proportion of enteric adenoviruses, possibly comprising previously unidentified or emerging types, are not detected by commercial diagnostic tests in South Africa.
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页码：1661 / 1663
页数：3
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