Chemically engineered persistent luminescence nanoprobes for bioimaging

被引：164

作者：

Lecuyer, Thomas ^{[1
,2
]}

Teston, Eliott ^{[1
,2
]}

Ramirez-Garcia, Gonzalo ^{[1
,2
]}

Maldiney, Thomas ^{[1
,2
]}

Viana, Bruno ^{[2
,3
]}

Seguin, Johanne ^{[1
,2
]}

Mignet, Nathalie ^{[1
,2
]}

Scherman, Daniel ^{[1
,2
]}

Richard, Cyrille ^{[1
,2
]}

机构：

[1] Univ Paris 05, Fac Sci Pharmaceut & Biol, INSERM, Sorbonne Paris Cite,UTCBS,CNRS,UMR 8258,U1022, F-75006 Paris, France

[2] Chim ParisTech, PSL, F-75005 Paris, France

[3] Chim ParisTech, CNRS UMR 8247, Inst Rech Chim Paris, F-75005 Paris, France

来源：

THERANOSTICS | 2016年 / 6卷 / 13期

关键词：

Nanoparticles; chemistry; surface coating; persistent luminescence and in vivo imaging; NEAR-INFRARED LUMINESCENCE; IN-VIVO; MULTIFUNCTIONAL NANOPARTICLES; OXIDE NANOPARTICLES; LASER-ABLATION; DRUG-DELIVERY; QUANTUM DOTS; LIVING CELLS; ULTRA-SMALL; RED;

D O I：

10.7150/thno.16589

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Imaging nanoprobes are a group of nanosized agents developed for providing improved contrast for bioimaging. Among various imaging probes, optical sensors capable of following biological events or progresses at the cellular and molecular levels are actually actively developed for early detection, accurate diagnosis, and monitoring of the treatment of diseases. The optical activities of nanoprobes can be tuned on demand by chemists by engineering their composition, size and surface nature. This review will focus on researches devoted to the conception of nanoprobes with particular optical properties, called persistent luminescence, and their use as new powerful bioimaging agents in preclinical assays.

引用

收藏

页码：2488 / 2524

页数：37

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