Guidelines for Acromegaly Management: An Update

被引:541
作者
Melmed, S. [1 ]
Colao, A. [2 ]
Barkan, A. [3 ]
Molitch, M. [4 ]
Grossman, A. B. [5 ]
Kleinberg, D. [6 ]
Clemmons, D. [7 ]
Chanson, P. [8 ,9 ]
Laws, E. [10 ]
Schlechte, J. [11 ]
Vance, M. L. [12 ]
Ho, K. [13 ]
Giustina, A. [14 ]
机构
[1] Cedars Sinai Med Ctr, Cedars Sinai Res Inst, Dept Med, Los Angeles, CA 90048 USA
[2] Univ Naples Federico II, Dept Mol & Clin Endocrinol & Oncol, I-80138 Naples, Italy
[3] Univ Michigan, Div Endocrinol & Metab, Med Ctr, Ann Arbor, MI 48109 USA
[4] Northwestern Univ, Endocrinol Clin, Feinberg Sch Med, Chicago, IL 60611 USA
[5] St Bartholomews Hosp, Dept Endocrinol, London EC1A 7BE, England
[6] NYU, Med Ctr, Dept Med, New York, NY 10016 USA
[7] Univ N Carolina, Div Endocrinol, Chapel Hill, NC 27599 USA
[8] Hop Bicetre, AP HP, Dept Endocrinol & Reprod Dis, F-94276 Le Kremlin Bicetre, France
[9] Univ Paris 11, F-94276 Le Kremlin Bicetre, France
[10] Brigham & Womens Hosp, Dept Neurosurg, Boston, MA 02115 USA
[11] Univ Iowa, Dept Internal Med, Iowa City, IA 52242 USA
[12] Univ Virginia, Dept Med, Charlottesville, VA 22904 USA
[13] Garvan Inst Med Res, Pituitary Res Unit, Sydney, NSW 2010, Australia
[14] Univ Brescia, Dept Internal Med, I-25121 Brescia, Italy
关键词
GROWTH-FACTOR-I; GAMMA-KNIFE RADIOSURGERY; PREOPERATIVE OCTREOTIDE TREATMENT; ACTING SOMATOSTATIN ANALOGS; DOPAMINE AGONIST THERAPY; LONG-TERM EFFICACY; QUALITY-OF-LIFE; FOLLOW-UP; PITUITARY-ADENOMAS; TRANSSPHENOIDAL SURGERY;
D O I
10.1210/jc.2008-2421
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective: The Acromegaly Consensus Group reconvened in November 2007 to update guidelines for acromegaly management. Participants: The meeting participants comprised 68 pituitary specialists, including neurosurgeons and endocrinologists with extensive experience treating patients with acromegaly. Evidence/Consensus Process: Goals of treatment and the appropriate imaging and biochemical and clinical monitoring of patients with acromegaly were enunciated, based on the available published evidence. Conclusions: The group developed a consensus on the approach to managing acromegaly including appropriate roles for neurosurgery, medical therapy, and radiation therapy in the management of these patients. (J Clin Endocrinol Metab 94: 1509-1517, 2009)
引用
收藏
页码:1509 / 1517
页数:9
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