The Effect of an Intravitreal Dexamethasone Implant for Cystoid Macular Edema in Retinitis Pigmentosa: A Case Report and Literature Review

被引：24
作者：
Ahn, Seong Joon [1 ,2 ]
Kim, Ko Eun [1 ,3 ]
Woo, Se Joon [1 ]
Park, Kyu Hyung [1 ]
机构：
[1] Seoul Natl Univ, Bundang Hosp, Dept Ophthalmol, Coll Med, Songnam 463707, Gyeonggi Do, South Korea
[2] Armed Forces Capital Hosp, Dept Ophthalmol, Songnam, South Korea
[3] Seoul Natl Univ, Coll Med, Seoul Natl Univ Hosp, Dept Ophthalmol, Seoul, South Korea
来源：
OPHTHALMIC SURGERY LASERS & IMAGING | 2014年 / 45卷 / 02期
关键词：
CHRONIC INFLAMMATORY REACTION; OPTICAL COHERENCE TOMOGRAPHY; ACETAZOLAMIDE; TRIAMCINOLONE; INJECTION; BREAKDOWN;
D O I：
10.3928/23258160-20140131-03
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
Intravitreal injection of a dexamethasone implant was used to treat a 24-year-old patient with retinitis pigmentosa (RP) who developed cystoid macular edema (CME) in both eyes that was refractory to oral acetazolamide and intravitreal bevacizumab treatment. After injection, best corrected visual acuity (BCVA) improved and central macular thickness decreased, but CME recurred in both eyes 6 months later. Although a second intravitreal dexamethasone implant injection resolved the CME and improved the BCVA, CME recurred in both eyes 6 months later. The intravitreal dexamethasone implant may be useful for CME in patients with RP, but its efficacy seems to be limited over time.
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收藏
页码：160 / 164
页数：5
相关论文
共 22 条
[1]   DEXAMETHASONE INTRAVITREAL IMPLANT FOR TREATMENT OF DIABETIC MACULAR EDEMA IN VITRECTOMIZED PATIENTS [J].
Boyer, David S. ;
Faber, David ;
Gupta, Sunil ;
Patel, Sunil S. ;
Tabandeh, Homayoun ;
Li, Xiao-Yan ;
Liu, Charlie C. ;
Lou, Jean ;
Whitcup, Scott M. .
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, 2011, 31 (05) :915-923
[2]  
COX SN, 1988, ARCH OPHTHALMOL-CHIC, V106, P1190
[3]   BREAKDOWN OF THE BLOOD-RETINAL BARRIERS AND CYSTOID MACULAR EDEMA [J].
CUNHAVAZ, JG ;
TRAVASSOS, A .
SURVEY OF OPHTHALMOLOGY, 1984, 28 :485-492
[4]  
FISHMAN GA, 1981, ARCH OPHTHALMOL-CHIC, V99, P1202
[5]   ACETAZOLAMIDE FOR TREATMENT OF CHRONIC MACULAR EDEMA IN RETINITIS PIGMENTOSA [J].
FISHMAN, GA ;
GILBERT, LD ;
FISCELLA, RG ;
KIMURA, AE ;
JAMPOL, LM .
ARCHIVES OF OPHTHALMOLOGY, 1989, 107 (10) :1445-1452
[6]   Vitreoretinal surgery for cystoid macular edema associated with retinitis pigmentosa [J].
García-Arumí, J ;
Martinez, V ;
Sararols, L ;
Corcostegui, B .
OPHTHALMOLOGY, 2003, 110 (06) :1164-1169
[7]   The prevalence of cystoid macular oedema in retinitis pigmentosa patients determined by optical coherence tomography [J].
Hajali, M. ;
Fishman, G. A. ;
Anderson, R. J. .
BRITISH JOURNAL OF OPHTHALMOLOGY, 2008, 92 (08) :1065-1068
[8]   Randomized, Sham-Controlled Trial of Dexamethasone Intravitreal Implant in Patients with Macular Edema Due to Retinal Vein Occlusion [J].
Haller, Julia A. ;
Bandello, Francesco ;
Belfort, Rubens, Jr. ;
Blumenkranz, Mark S. ;
Gillies, Mark ;
Heier, Jeffrey ;
Loewenstein, Anat ;
Yoon, Young-Hee ;
Jacques, Marie-Louise ;
Jiao, Jenny ;
Li, Xiao-Yan ;
Whitcup, Scott M. .
OPHTHALMOLOGY, 2010, 117 (06) :1134-U164
[9]   Association of antiretinal antibodies and cystoid macular edema in patients with retinitis pigmentosa [J].
Heckenlively, JR ;
Jordan, BL ;
Aptsiauri, N .
AMERICAN JOURNAL OF OPHTHALMOLOGY, 1999, 127 (05) :565-573
[10]   Optical coherence tomography of cystoid macular edema associated with retinitis pigmentosa [J].
Hirakawa, H ;
Iijima, H ;
Gohdo, T ;
Tsukahara, S .
AMERICAN JOURNAL OF OPHTHALMOLOGY, 1999, 128 (02) :185-191
123