Refractory Whipple's disease with anaemia: First lessons from capsule endoscopy

被引：18

作者：

Fritscher-Ravens, A

Swain, CP

von Herbay, A

机构：

[1] St Marys Hosp, Endoscopy Unit, London, England

[2] Homerton Univ Hosp, Endoscopy Unit, London, England

[3] Univ Heidelberg, Inst Pathol, D-6900 Heidelberg, Germany

来源：

ENDOSCOPY | 2004年 / 36卷 / 07期

关键词：

D O I：

10.1055/s-2004-814537

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Whipple's disease is a chronic multisystem disorder caused by infection with the rod-shaped bacterium, Tropheryma whippelii. We report the case of a 65-year-old woman with intestinal Whipple's disease that had been refractory to monotherapy with a number of antibiotics over a 2-year period. The patient then presented with watery diarrhoea, cachexia (body mass index 18 kg/m(2)) and chronic anaemia (haemoglobin 7.6 g/dl). Wireless capsule endoscopy showed that the disease affected the entire small intestine. Focal occult areas of bleeding were observed in different parts of the jejunum. The capsule's transit time through the small intestine was 2 hours 43 minutes. Capsule endoscopy allows novel insights into the pathophysiology of Whipple's disease.

引用

页码：659 / 662

页数：4

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