Pulmonary Arteriovenous Malformations and Embolic Complications in Patients With Hereditary Hemorrhagic Telangiectasia

被引：20

作者：

Angriman, Federico ^{[1
]}

Ferreyro, Bruno L. ^{[1
]}

Wainstein, Esteban J. ^{[2
]}

Serra, Marcelo M. ^{[1
,3
]}

机构：

[1] Univ Buenos Aires, Hosp Italian Buenos Aires, Dept Med Interna, Buenos Aires, DF, Argentina

[2] Hosp Italian Buenos Aires, Dept Med Resp, Buenos Aires, DF, Argentina

[3] Hosp Italian Buenos Aires, Unidad THH, Buenos Aires, DF, Argentina

来源：

ARCHIVOS DE BRONCONEUMOLOGIA | 2014年 / 50卷 / 07期

关键词：

Embolism; Hereditary hemorrhagic telangiectasia; Pulmonary arteriovenous malformation; Stroke;

D O I：

10.1016/j.arbres.2013.08.006

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Patients with hereditary hemorrhagic telangiectasia (HHT) and pulmonary arteriovenous malformation (PAVM) face higher risk of embolic complications. It is not clear whether poor outcomes are related to PAVM severity or pulmonary symptoms. Furthermore, there is currently no available data on HI-IT patients in Argentina. We conducted a cross sectional study in a teaching hospital in Buenos Aires, Argentina. We describe baseline characteristics of HHT and compare the prevalence of embolic complications in patients with significant PAVM compared to patients without significant PAVM. One hundred and eight consecutive patients were included. Significant PAVM was defined as: contrast echocardiography grade 2 or greater; bilateral PAVM or feeding artery bigger than 3 mm; or previous PAVM treatment. Primary composite outcome was defined as: cerebrovascular accident, cerebral abscess or peripheral embolism. 20% of participants had embolic complications, the most frequent one was stroke. Embolic complications were associated with significant PAVM and respiratory symptoms. (C) 2013 SEPAR. Published by Elsevier Espana, S.L. All rights reserved.

引用

页码：301 / 304

页数：4

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