Inflammation, C- Reactive Protein, and Cardiovascular Disease

被引:41
作者
Ridker, Paul M. [1 ]
机构
[1] Harvard Univ, Brigham & Womens Hosp, Sch Med, Ctr Cardiovasc Dis Prevent, Boston, MA 02115 USA
关键词
Editorials; atherothrombosis; C-reactive protein; clinical trials; inflammation; interleukin-1; interleukin-6; CORONARY-HEART-DISEASE; CHOLESTEROL; EVENTS; RATIONALE; OUTCOMES; DESIGN; RISK;
D O I
10.1161/CIRCRESAHA.114.303215
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:594 / 595
页数:2
相关论文
共 18 条
[1]   Creating controversy where none exists: the important role of C-reactive protein in the CARE, AFCAPS/TexCAPS, PROVE IT, REVERSAL, A to Z, JUPITER, HEART PROTECTION, and ASCOT trials [J].
Braunwald, Eugene .
EUROPEAN HEART JOURNAL, 2012, 33 (04) :430-432
[2]   NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals [J].
Duewell, Peter ;
Kono, Hajime ;
Rayner, Katey J. ;
Sirois, Cherilyn M. ;
Vladimer, Gregory ;
Bauernfeind, Franz G. ;
Abela, George S. ;
Franchi, Luigi ;
Nunez, Gabriel ;
Schnurr, Max ;
Espevik, Terje ;
Lien, Egil ;
Fitzgerald, Katherine A. ;
Rock, Kenneth L. ;
Moore, Kathryn J. ;
Wright, Samuel D. ;
Hornung, Veit ;
Latz, Eicke .
NATURE, 2010, 464 (7293) :1357-U7
[3]   Rationale and design of the Cardiovascular Inflammation Reduction Trial: A test of the inflammatory hypothesis of atherothrombosis [J].
Everett, Brendan M. ;
Pradhan, Aruna D. ;
Solomon, Daniel H. ;
Paynter, Nina ;
MacFadyen, Jean ;
Zaharris, Elaine ;
Gupta, Milan ;
Clearfield, Michael ;
Libby, Peter ;
Hasan, Ahmed A. K. ;
Glynn, Robert J. ;
Ridker, Paul M. .
AMERICAN HEART JOURNAL, 2013, 166 (02) :199-+
[4]   C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis [J].
Kaptoge, Stephen ;
Di Angelantonio, Emanuele ;
Lowe, Gordon ;
Pepys, Mark B. ;
Thompson, Simon G. ;
Collins, Rory ;
Danesh, John ;
Tipping, R. W. ;
Ford, C. E. ;
Pressel, S. L. ;
Walldius, G. ;
Jungner, I. ;
Folsom, A. R. ;
Chambless, L. ;
Ballantyne, C. M. ;
Panagiotakos, D. ;
Pitsavos, C. ;
Chrysohoou, C. ;
Stefanadis, C. ;
Knuiman, M. W. ;
Goldbourt, U. ;
Benderly, M. ;
Tanne, D. ;
Whincup, P. ;
Wannamethee, S. G. ;
Morris, R. W. ;
Kiechl, S. ;
Willeit, J. ;
Mayr, A. ;
Schett, G. ;
Wald, N. ;
Ebrahim, S. ;
Lawlor, D. ;
Yarnell, J. ;
Gallacher, J. ;
Casiglia, E. ;
Tikhonoff, V. ;
Nietert, P. J. ;
Sutherland, S. E. ;
Bachman, D. L. ;
Keil, J. E. ;
Cushman, M. ;
Psaty, B. M. ;
Tracy, R. ;
Tybjaerg-Hansen, A. ;
Nordestgaard, B. G. ;
Zacho, J. ;
Frikke-Schmidt, R. ;
Giampaoli, S. ;
Palmieri, L. .
LANCET, 2010, 375 (9709) :132-140
[5]   Infusion of Pharmaceutical-Grade Natural Human C-Reactive Protein Is Not Proinflammatory in Healthy Adult Human Volunteers [J].
Lane, Thirusha ;
Wassef, Nancy ;
Poole, Stephen ;
Mistry, Yogesh ;
Lachmann, Helen J. ;
Gillmore, Julian D. ;
Hawkins, Philip N. ;
Pepys, Mark B. .
CIRCULATION RESEARCH, 2014, 114 (04) :672-676
[6]   Progress and challenges in translating the biology of atherosclerosis [J].
Libby, Peter ;
Ridker, Paul M. ;
Hansson, Goran K. .
NATURE, 2011, 473 (7347) :317-325
[7]   THE PROGNOSTIC VALUE OF C-REACTIVE PROTEIN AND SERUM AMYLOID-A PROTEIN IN SEVERE UNSTABLE ANGINA [J].
LIUZZO, G ;
BIASUCCI, LM ;
GALLIMORE, JR ;
GRILLO, RL ;
REBUZZI, AG ;
PEPYS, MB ;
MASERI, A .
NEW ENGLAND JOURNAL OF MEDICINE, 1994, 331 (07) :417-424
[9]   Statin therapy, LDL cholesterol, C-reactive protein, and coronary artery disease [J].
Nissen, SE ;
Tuzcu, EM ;
Schoenhagen, P ;
Crowe, T ;
Sasiela, WJ ;
Tsai, J ;
Orazem, J ;
Magorien, RD ;
O'Shaughnessy, C ;
Ganz, P .
NEW ENGLAND JOURNAL OF MEDICINE, 2005, 352 (01) :29-38
[10]   Targeting C-reactive protein for the treatment of cardiovascular disease [J].
Pepys, MB ;
Hirschfield, GM ;
Tennent, GA ;
Gallimore, JR ;
Kahan, MC ;
Bellotti, V ;
Hawkins, PN ;
Myers, RM ;
Smith, MD ;
Polara, A ;
Cobb, AJA ;
Ley, SV ;
Aquilina, JA ;
Robinson, CV ;
Sharif, I ;
Gray, GA ;
Sabin, CA ;
Jenvey, MC ;
Kolstoe, SE ;
Thompson, D ;
Wood, SP .
NATURE, 2006, 440 (7088) :1217-1221