Treatment of Pediatric Multiple Sclerosis

被引：4
作者：
Kornek, Barbara [1 ]
机构：
[1] Med Univ Vienna, Dept Neurol, A-1090 Vienna, Austria
来源：
NEUROPEDIATRICS | 2013年 / 44卷 / 06期
关键词：
multiple sclerosis; pediatric; disease-modifying therapy; DISEASE-MODIFYING THERAPIES; INTERFERON BETA-1A THERAPY; PLACEBO-CONTROLLED TRIAL; PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY; TERM-FOLLOW-UP; INTRAMUSCULAR INTERFERON; CONTROLLED PHASE-3; DOUBLE-BLIND; RANDOMIZED-TRIAL; ORAL FINGOLIMOD;
D O I：
10.1055/s-0033-1359308
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Multiple sclerosis (MS) in children and adolescents has received increased attention during the past decade. Although not tested in randomized placebo-controlled trials, first-line disease-modifying therapies are widely used in patients with MS who are younger than 18 years. This review summarizes current treatment practices, possible future treatment options, and gives insight into special problems in the treatment of pediatric patients with MS.
引用
收藏
页码：309 / 313
页数：5
相关论文
共 88 条
  • [1] Cognitive and psychosocial features in childhood and juvenile MS Two-year follow-up
    Amato, M. P.
    Goretti, B.
    Ghezzi, A.
    Lori, S.
    Zipoli, V.
    Moiola, L.
    Falautano, M.
    De Caro, M. F.
    Viterbo, R.
    Patti, F.
    Vecchio, R.
    Pozzilli, C.
    Bianchi, V.
    Roscio, M.
    Martinelli, V.
    Comi, G.
    Portaccio, E.
    Trojano, M.
    [J]. NEUROLOGY, 2010, 75 (13) : 1134 - 1140
  • [2] Safety and tolerability of interferon beta-1b in pediatric multiple sclerosis
    Banwell, B
    Reder, AT
    Krupp, L
    Tenembaum, S
    Eraksoy, M
    Alexey, B
    Pohl, D
    Freedman, M
    Schelensky, L
    Antonijevic, I
    [J]. NEUROLOGY, 2006, 66 (04) : 472 - 476
  • [3] Banwell Brenda, 2005, Expert Rev Neurother, V5, P391, DOI 10.1586/14737175.5.3.391
  • [4] Multiple sclerosis in children: clinical diagnosis, therapeutic strategies, and future directions
    Banwell, Brenda
    Ghezzi, Angelo
    Bar-Or, Amit
    Mikaeloff, Yann
    Tardieu, Marc
    [J]. LANCET NEUROLOGY, 2007, 6 (10) : 887 - 902
  • [5] Therapies for multiple sclerosis: considerations in the pediatric patient
    Banwell, Brenda
    Bar-Or, Amit
    Giovannoni, Gavin
    Dale, Russell C.
    Tardieu, Marc
    [J]. NATURE REVIEWS NEUROLOGY, 2011, 7 (02) : 109 - 122
  • [6] Intramuscular interferon beta-1a therapy in patients with relapsing-remitting multiple sclerosis: a 15-year follow-up study
    Bermel, R. A.
    Weinstock-Guttman, B.
    Bourdette, D.
    Foulds, P.
    You, X.
    Rudick, R. A.
    [J]. MULTIPLE SCLEROSIS JOURNAL, 2010, 16 (05) : 588 - 596
  • [7] Risk of Natalizumab-Associated Progressive Multifocal Leukoencephalopathy
    Bloomgren, Gary
    Richman, Sandra
    Hotermans, Christophe
    Subramanyam, Meena
    Goelz, Susan
    Natarajan, Amy
    Lee, Sophia
    Plavina, Tatiana
    Scanlon, James V.
    Sandrock, Alfred
    Bozic, Carmen
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2012, 366 (20) : 1870 - 1880
  • [8] Early onset multiple sclerosis - A longitudinal study
    Boiko, A
    Vorobeychik, G
    Paty, D
    Devonshire, V
    Sadovnick, D
    [J]. NEUROLOGY, 2002, 59 (07) : 1006 - 1010
  • [9] Natalizumab treatment in pediatric multiple sclerosis: A case report
    Borriello, Giovanna
    Prosperini, Luca
    Luchetti, Anna
    Pozzilli, Carlo
    [J]. EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY, 2009, 13 (01) : 67 - 71
  • [10] Bozic C, 2011, NEUROLOGY, V76, pA598
123456789