USA stockpiling of remdesivir: How should the world respond?

被引:2
作者
Dawoud, Dalia [1 ]
Chalkidou, Kalipso [2 ,3 ]
Sullivan, Richard [4 ]
Ruiz, Francis J. [5 ]
Adler, Amanda [6 ]
机构
[1] Cairo Univ, Fac Pharm, Cairo, Egypt
[2] Ctr Global Dev, London, England
[3] Imperial Coll London, Practice Global Hlth, London, England
[4] Kings Coll London, Canc & Global Hlth, London, England
[5] Imperial Coll London, Ctr Global Dev, London, England
[6] Univ Oxford, NICE Technol Appraisal Comm B, Oxford, England
关键词
antiviral; coronavirus; COVID-19; dexamethasone; remdesivir; SARS-CoV-2; stockpiling;
D O I
10.2217/cer-2020-0174
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
The race to find an effective treatment for coronavirus disease 2019 (COVID-19) is still on, with only two treatment options currently authorized for emergency use and/or recommended for patients hospitalized with severe respiratory symptoms: low-dose dexamethasone and remdesivir. The USA decision to stockpile the latter has resulted in widespread condemnation and in similar action being taken by some other countries. In this commentary we discuss whether stockpiling remdesivir is justified in light of the currently available evidence.
引用
收藏
页码:1243 / 1246
页数:4
相关论文
共 18 条
  • [11] Case-Fatality Rate and Characteristics of Patients Dying in Relation to COVID-19 in Italy
    Onder, Graziano
    Rezza, Giovanni
    Brusaferro, Silvio
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2020, 323 (18): : 1775 - 1776
  • [12] Pan H, 2020, REPURPOSED ANTIVIRAL, DOI 10.1101/2020.10.15.20209817
  • [13] Clinical evidence for repurposing chloroquine and hydroxychloroquine as antiviral agents: a systematic review
    Rodrigo, C.
    Fernando, S. D.
    Rajapakse, S.
    [J]. CLINICAL MICROBIOLOGY AND INFECTION, 2020, 26 (08) : 979 - 987
  • [14] Senanayake SL, 2020, FUTURE DRUG DISCOV, V2, DOI 10.4155/fdd-2020-0010
  • [15] Shah HA, 2020, DEXAMETHASONE SEVERE
  • [16] Drug treatments for covid-19: living systematic review and network meta-analysis
    Siemieniuk, Reed A. C.
    Bartoszko, Jessica J.
    Ge, Long
    Zeraatkar, Dena
    Izcovich, Ariel
    Pardo-Hernandez, Hector
    Rochwerg, Bram
    Lamontagne, Francois
    Han, Mi Ah
    Kum, Elena
    Liu, Qin
    Agarwal, Arnav
    Agoritsas, Thomas
    Alexander, Paul
    Chu, Derek K.
    Couban, Rachel
    Darzi, Andrea
    Devji, Tahira
    Fang, Bo
    Fang, Carmen
    Flottorp, Signe Agnes
    Foroutan, Farid
    Heels-Ansdell, Diane
    Honarmand, Kimia
    Hou, Liangying
    Hou, Xiaorong
    Ibrahim, Quazi
    Loeb, Mark
    Marcucci, Maura
    McLeod, Shelley L.
    Motaghi, Sharhzad
    Murthy, Srinivas
    Mustafa, Reem A.
    Neary, John D.
    Qasim, Anila
    Rada, Gabriel
    Bin Riaz, Irbaz
    Sadeghirad, Behnam
    Sekercioglu, Nigar
    Sheng, Lulu
    Switzer, Charlotte
    Tendal, Britta
    Thabane, Lehana
    Tomlinson, George
    Turner, Tari
    Vandvik, Per O.
    Vernooij, Robin Wm
    Viteri-Garcia, Andres
    Wang, Ying
    Yao, Liang
    [J]. BMJ-BRITISH MEDICAL JOURNAL, 2020, 370
  • [17] Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial
    Wang, Yeming
    Zhang, Dingyu
    Du, Guanhua
    Du, Ronghui
    Zhao, Jianping
    Jin, Yang
    Fu, Shouzhi
    Gao, Ling
    Cheng, Zhenshun
    Lu, Qiaofa
    Hu, Yi
    Luo, Guangwei
    Wang, Ke
    Lu, Yang
    Li, Huadong
    Wang, Shuzhen
    Ruan, Shunan
    Yang, Chengqing
    Mei, Chunlin
    Wang, Yi
    Ding, Dan
    Wu, Feng
    Tang, Xin
    Ye, Xianzhi
    Ye, Yingchun
    Liu, Bing
    Yang, Jie
    Yin, Wen
    Wang, Aili
    Fan, Guohui
    Zhou, Fei
    Liu, Zhibo
    Gu, Xiaoying
    Xu, Jiuyang
    Shang, Lianhan
    Zhang, Yi
    Cao, Lianjun
    Guo, Tingting
    Wan, Yan
    Qin, Hong
    Jiang, Yushen
    Jaki, Thomas
    Hayden, Frederick G.
    Horby, Peter W.
    Cao, Bin
    Wang, Chen
    [J]. LANCET, 2020, 395 (10236) : 1569 - 1578
  • [18] Whittington, 2020, ALTERNATIVE PRICING