USA stockpiling of remdesivir: How should the world respond?

被引:2
作者
Dawoud, Dalia [1 ]
Chalkidou, Kalipso [2 ,3 ]
Sullivan, Richard [4 ]
Ruiz, Francis J. [5 ]
Adler, Amanda [6 ]
机构
[1] Cairo Univ, Fac Pharm, Cairo, Egypt
[2] Ctr Global Dev, London, England
[3] Imperial Coll London, Practice Global Hlth, London, England
[4] Kings Coll London, Canc & Global Hlth, London, England
[5] Imperial Coll London, Ctr Global Dev, London, England
[6] Univ Oxford, NICE Technol Appraisal Comm B, Oxford, England
关键词
antiviral; coronavirus; COVID-19; dexamethasone; remdesivir; SARS-CoV-2; stockpiling;
D O I
10.2217/cer-2020-0174
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
The race to find an effective treatment for coronavirus disease 2019 (COVID-19) is still on, with only two treatment options currently authorized for emergency use and/or recommended for patients hospitalized with severe respiratory symptoms: low-dose dexamethasone and remdesivir. The USA decision to stockpile the latter has resulted in widespread condemnation and in similar action being taken by some other countries. In this commentary we discuss whether stockpiling remdesivir is justified in light of the currently available evidence.
引用
收藏
页码:1243 / 1246
页数:4
相关论文
共 18 条
  • [1] [Anonymous], 2020, STAFF WRITER
  • [2] Remdesivir for the Treatment of Covid-19-Final Report
    Beigel, John H.
    Tomashek, Kay M.
    Dodd, Lori E.
    Mehta, Aneesh K.
    Zingman, Barry S.
    Kalil, Andre C.
    Hohmann, Elizabeth
    Chu, Helen Y.
    Luetkemeyer, Annie
    Kline, Susan
    de Castilla, Diego Lopez
    Finberg, Robert W.
    Dierberg, Kerry
    Tapson, Victor
    Hsieh, Lanny
    Patterson, Thomas F.
    Paredes, Roger
    Sweeney, Daniel A.
    Short, William R.
    Touloumi, Giota
    Lye, David Chien
    Ohmagari, Norio
    Oh, Myoung-don
    Ruiz-Palacios, Guillermo M.
    Benfield, Thomas
    Faetkenheuer, Gerd
    Kortepeter, Mark G.
    Atmar, Robert L.
    Creech, C. Buddy
    Lundgren, Jens
    Babiker, Abdel G.
    Pett, Sarah
    Neaton, James D.
    Burgess, Timothy H.
    Bonnett, Tyler
    Green, Michelle
    Makowski, Mat
    Osinusi, Anu
    Nayak, Seema
    Lane, H. Clifford
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2020, 383 (19) : 1813 - 1826
  • [3] Boseley S., 2020, THE GUARDIAN, DOI [10.1126/science.abe6380, DOI 10.1126/SCIENCE.ABE6380]
  • [4] Brophy, 2020, US PURCHASES WORLD S
  • [5] Remdesivir: A Review of Its Discovery and Development Leading to Emergency Use Authorization for Treatment of COVID-19
    Eastman, Richard T.
    Roth, Jacob S.
    Brimacombe, Kyle R.
    Simeonov, Anton
    Shen, Min
    Patnaik, Samarjit
    Hall, Matthew D.
    [J]. ACS CENTRAL SCIENCE, 2020, 6 (05) : 672 - 683
  • [6] Gilead Sciences, 2020, CO STAT GIL SCI STAT
  • [7] Dexamethasone in Hospitalized Patients with Covid-19
    Horby, Peter
    Lim, Wei Shen
    Emberson, Jonathan R.
    Mafham, Marion
    Bell, Jennifer L.
    Linsell, Louise
    Staplin, Natalie
    Brightling, Christopher
    Ustianowski, Andrew
    Elmahi, Einas
    Prudon, Benjamin
    Green, Christopher
    Felton, Timothy
    Chadwick, David
    Rege, Kanchan
    Fegan, Christopher
    Chappell, Lucy C.
    Faust, Saul N.
    Jaki, Thomas
    Jeffery, Katie
    Montgomery, Alan
    Rowan, Kathryn
    Juszczak, Edmund
    Baillie, J. Kenneth
    Haynes, Richard
    Landray, Martin J.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2021, 384 (08) : 693 - 704
  • [8] John Hopskins University of Medicine, 2020, COVID 19 DASHB CTR S
  • [9] Leegwater E, 2020, CLIN INFECT DIS, DOI 10.1093/cid/ciaa88
  • [10] Quarantine alone or in combination with other public health measures to control COVID-19: a rapid review
    Nussbaumer-Streit, Barbara
    Mayr, Verena
    Dobrescu, Andreea Iulia
    Chapman, Andrea
    Persad, Emma
    Klerings, Irma
    Wagner, Gernot
    Siebert, Uwe
    Christof, Claudia
    Zachariah, Casey
    Gartlehner, Gerald
    [J]. COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2020, (04):