Novel ZnCl2-catalyzed one-pot multicomponent synthesis of 2-amino-3,5-dicarbonitrile-6-thio-pyridines

被引:91
作者
Sridhar, Madabhushi [1 ]
Ramanaiah, Beeram C. [1 ]
Narsaiah, Chinthala [1 ]
Mahesh, Bellam [1 ]
Kumaraswamy, Mudam [1 ]
Mallu, Kishore K. R. [1 ]
Ankathi, Vishnu M. [1 ]
Rao, Pamulaparty Shanthan [1 ]
机构
[1] Indian Inst Chem Technol, Fluoroorgan Div, Hyderabad 500007, Andhra Pradesh, India
关键词
2-Amino-3,5-dicarbonitrile-6-thio-pyridines; Multicomponent reaction; Lewis acid catalysis; ZnCl2; Microwave reaction; 3-COMPONENT SYNTHESIS; DRUG DISCOVERY; ONE-STEP; ADENOSINE; DERIVATIVES; INHIBITION; CHEMISTRY; PYRIDINES; RECEPTOR; PROFILE;
D O I
10.1016/j.tetlet.2009.04.051
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
ZnCl2-catalyzed one-pot multicomponent synthesis of 2-amino-3,5-dicarbonitrile-6-thio-pyridines under microwave heating and conventional heating is described. (c) 2009 Elsevier Ltd. All rights reserved.
引用
收藏
页码:3897 / 3900
页数:4
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