Organosilicon(IV) complexes with therapeutically relevant ligands (LH)-H-n, where n = 1 to 3, have been synthesized by the condensation of 1,3-dihdyro-3-[2-(phenyl)-2-oxo-ethylidene]-2H indol-2-one, 3-(indolin-2-one) and 1-acetylferrocene with thiosemicarbazide. The ligands and their complexes have been characterized by elemental analyses, molecular weight determinations, IR, UV and H-1 NMR spectral studies. The ligands and their corresponding silicon complexes were screened for their antimicrobial activity on different species of bacteria and fungi and were found active in this respect.
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Natl Res Ctr, Pharmaceut & Drug Ind Res Div, Chem Nat & Microbial Prod Dept, 33 Bohouth St,POB 12622, Giza, EgyptNatl Res Ctr, Pharmaceut & Drug Ind Res Div, Chem Nat & Microbial Prod Dept, 33 Bohouth St,POB 12622, Giza, Egypt
Kassem, Asmaa F.
Abbas, Eman M. H.
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Natl Res Ctr, Pharmaceut & Drug Ind Res Div, Chem Nat & Microbial Prod Dept, 33 Bohouth St,POB 12622, Giza, EgyptNatl Res Ctr, Pharmaceut & Drug Ind Res Div, Chem Nat & Microbial Prod Dept, 33 Bohouth St,POB 12622, Giza, Egypt
Abbas, Eman M. H.
Al-Qurashi, Nadia T.
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Umm Al Qura Univ, Univ Coll Adam, Dept Basic Sci, Mecca, Almukkarramah, Saudi ArabiaNatl Res Ctr, Pharmaceut & Drug Ind Res Div, Chem Nat & Microbial Prod Dept, 33 Bohouth St,POB 12622, Giza, Egypt
Al-Qurashi, Nadia T.
Farghaly, Thoraya A.
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Cairo Univ, Fac Sci, Dept Chem, Giza 1263, Egypt
Umm Al Qura Univ, Fac Appl Sci, Dept Chem, Mecca 21514, Almukkarramah, Saudi ArabiaNatl Res Ctr, Pharmaceut & Drug Ind Res Div, Chem Nat & Microbial Prod Dept, 33 Bohouth St,POB 12622, Giza, Egypt