Measurement of cardiac output by use of noninvasively measured transient hemodilution curves with photoacoustic technology

被引:7
作者
Kang, Dongyel [1 ,2 ]
Huang, Qiaojian [1 ]
Li, Youzhi [1 ]
机构
[1] Covidien Resp & Monitoring Solut, Adv Technol, Boulder, CO 80301 USA
[2] HanBat Natl Univ, Taejon, South Korea
关键词
THERAPY;
D O I
10.1364/BOE.5.001445
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
We present the theoretical basis and experimental verification for cardiac output measurements using noninvasively measured hemodilution curves afforded with an indicator dilution technique and the emerging photoacoustic technology. A photoacoustic system noninvasively tracks a transient hemodilution effect induced by a bolus of isotonic saline as an indicator. As a result, a photoacoustic indicator dilution curve is obtained, which allows to estimate cardiac output from the developed algorithm. The experiments with a porcine blood circulatory phantom system demonstrated the feasibility of this technology towards the development of a noninvasive cardiac output measurement system for patient monitoring. (C) 2014 Optical Society of America
引用
收藏
页码:1445 / 1452
页数:8
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