The Role of the Pericardium in Heart Failure Implications for Pathophysiology and Treatment

被引：142

作者：

Borlaug, Barry A. ^{[1
]}

Reddy, Yogesh N., V ^{[1
]}

机构：

[1] Mayo Clin, Dept Cardiovasc Med, Rochester, MN USA

来源：

JACC-HEART FAILURE | 2019年 / 7卷 / 07期

基金：

美国国家卫生研究院;

关键词：

heart failure; hemodynamics; pericardium; VENTRICULAR DIASTOLIC PRESSURE; RIGHT ATRIAL PRESSURE; VOLUME; CONSTRAINT; MECHANISM; HYPERTENSION; ANGIOTENSIN; DYSFUNCTION; CAPACITANCE; EXERCISE;

D O I：

10.1016/j.jchf.2019.03.021

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The elastic pericardium exerts a compressive contact force on the surface of the myocardium that becomes more substantial when heart volume increases, as in patients with various forms of heart failure (HF). Pericardial restraint plays an important role in determining hemodynamics and ventricular function in both health and disease. This review discusses the physiology of pericardial restraint in HF and explores the question of whether it can be targeted indirectly through medical interventions or directly through a number of existing and future therapies. (C) 2019 by the American College of Cardiology Foundation.

引用

收藏

页码：574 / 585

页数：12

相关论文

共 48 条

[1] The Hemodynamic Basis of Exercise Intolerance in Tricuspid Regurgitation [J].

Andersen, Mads J. ;

Nishimura, Rick A. ;

Borlaug, Barry A. .

CIRCULATION-HEART FAILURE, 2014, 7 (06) :911-U76

[2] EXTERNAL-PRESSURE OF UNDISTURBED LEFT-VENTRICLE [J].

APPLEGATE, RJ ;

SANTAMORE, WP ;

KLOPFENSTEIN, HS ;

LITTLE, WC .

AMERICAN JOURNAL OF PHYSIOLOGY, 1990, 258 (04) :H1079-H1086

[3] RESTRAINING EFFECT OF INTACT PERICARDIUM DURING ACUTE VOLUME LOADING [J].

APPLEGATE, RJ ;

JOHNSTON, WE ;

VINTENJOHANSEN, J ;

KLOPFENSTEIN, HS ;

LITTLE, WC .

AMERICAN JOURNAL OF PHYSIOLOGY, 1992, 262 (06) :H1725-H1733

[4] INFLUENCE OF THE PERICARDIUM ON RIGHT AND LEFT-VENTRICULAR FILLING IN THE DOG [J].

ASSANELLI, D ;

LEW, WYW ;

SHABETAI, R ;

LEWINTER, MM .

JOURNAL OF APPLIED PHYSIOLOGY, 1987, 63 (03) :1025-1032

[5] Diastolic ventricular interaction in chronic heart failure [J].

Atherton, JJ ;

Moore, TD ;

Lele, SS ;

Thomson, HL ;

Galbraith, AJ ;

Belenkie, I ;

Tyberg, JV ;

Frenneaux, MP .

LANCET, 1997, 349 (9067) :1720-1724

[6] EFFECTS OF VOLUME LOADING DURING EXPERIMENTAL ACUTE PULMONARY-EMBOLISM [J].

BELENKIE, I ;

DANI, R ;

SMITH, ER ;

TYBERG, JV .

CIRCULATION, 1989, 80 (01) :178-188

[7] THE EFFECTS OF LYING POSITION ON VENTRICULAR VOLUME IN CONGENITAL ABSENCE OF THE PERICARDIUM [J].

BEPPU, S ;

NAITO, H ;

MATSUHISA, M ;

MIYATAKE, K ;

NIMURA, Y .

AMERICAN HEART JOURNAL, 1990, 120 (05) :1159-1166

[8] Left ventricular pacing minimizes diastolic ventricular interaction, allowing improved preload-dependent systolic performance [J].

Bleasdale, RA ;

Turner, MS ;

Mumford, CE ;

Steendijk, P ;

Paul, V ;

Tyberg, JV ;

Morris-Thurgood, JA ;

Frenneaux, MP .

CIRCULATION, 2004, 110 (16) :2395-2400

[9] Pericardiotomy Enhances Left Ventricular Diastolic Reserve With Volume Loading in Humans Implications for the Surgical Management of Heart Failure With Preserved Ejection Fraction [J].

Borlaug, Barry A. ;

Schaff, Hartzell V. ;

Pochettino, Alberto ;

Pedrotty, Dawn M. ;

Asirvatham, Samuel J. ;

Abel, Martin D. ;

Carter, Rickey E. ;

Mauermann, William J. .

CIRCULATION, 2018, 138 (20) :2295-2297

[10] Percutaneous Pericardial Resection A Novel Potential Treatment for Heart Failure With Preserved Ejection Fraction [J].

Borlaug, Barry A. ;

Carter, Rickey E. ;

Melenovsky, Vojtech ;

DeSimone, Christopher V. ;

Gaba, Prakriti ;

Killu, Ammar ;

Naksuk, Niyada ;

Lerman, Lilach ;

Asirvatham, Samuel J. .

CIRCULATION-HEART FAILURE, 2017, 10 (04)

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