Recent advances in the synthesis of pyrroles by multicomponent reactions

被引:656
作者
Estevez, Veronica [1 ]
Villacampa, Mercedes [1 ]
Menendez, J. Carlos [1 ]
机构
[1] Univ Complutense, Fac Farm, Dept Quim Organ & Farmaceut, E-28040 Madrid, Spain
关键词
ONE-POT SYNTHESIS; HIGHLY SUBSTITUTED PYRROLES; PROMOTED 3-COMPONENT REACTION; POLYSUBSTITUTED PYRROLES; 1,3-DICARBONYL COMPOUNDS; FUNCTIONALIZED PYRROLES; PROPARGYLIC ALCOHOLS; CONVENIENT SYNTHESIS; PRIMARY AMINES; EFFICIENT;
D O I
10.1039/c3cs60015g
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Pyrrole is one of the most important one-ring heterocycles. The ready availability of suitably substituted and functionalized pyrrole derivatives is essential for the progress of many branches of science, including biology and materials science. Access to this key heterocycle by multicomponent routes is particularly attractive in terms of synthetic efficiency, and also from the environmental point of view. We update here our previous review on this topic by describing the progress made in this area in the period between mid-2009 and the end of 2013.
引用
收藏
页码:4633 / 4657
页数:25
相关论文
共 114 条
  • [21] One-Pot Three-Component Synthesis of Tetrasubstituted N-H Pyrroles from Secondary Propargylic Alcohols, 1,3-Dicarbonyl Compounds and tert-Butyl Carbamate
    Cadierno, Victorio
    Gimeno, Jose
    Nebra, Noel
    [J]. JOURNAL OF HETEROCYCLIC CHEMISTRY, 2010, 47 (01) : 233 - 236
  • [22] Synthesis of 2,3,4-trisubstituted pyrroles via a facile reaction of vinyl azides and tosylmethyl isocyanide
    Chen, Wenteng
    Shao, Jiaan
    Li, Zhi
    Giulianotti, Marc A.
    Yu, Yongping
    [J]. CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 2012, 90 (02): : 214 - 221
  • [23] The marinopyrroles
    Clive, Derrick L. J.
    Cheng, Ping
    [J]. TETRAHEDRON, 2013, 69 (25) : 5067 - 5078
  • [24] A Simple and Efficient Metal-Free Synthesis of Tetrasubstituted Pyrroles by Iodine-Catalyzed Four-Component Coupling Reaction of Aldehydes, Amines, Dialkyl Acetylenedicarboxylates, and Nitromethane
    Das, Biswanath
    Bhunia, Nisith
    Lingaiah, Maram
    [J]. SYNTHESIS-STUTTGART, 2011, (21): : 3471 - 3474
  • [25] An Efficient New Method for the Synthesis of Polysubstituted Pyrroles
    Das, Biswanath
    Reddy, Gandolla Chinna
    Balasubramanyam, Penagaluri
    Veeranjaneyulu, Boyapati
    [J]. SYNTHESIS-STUTTGART, 2010, (10): : 1625 - 1628
  • [26] Exploitation of Dual Character of CN Moiety in the Synthesis of Uniquely Decorated 3H-Pyrroles: A Rare Observation
    Das, Paramita
    Ray, Suman
    Mukhopadhyay, Chhanda
    [J]. ORGANIC LETTERS, 2013, 15 (22) : 5622 - 5625
  • [27] Recent developments in asymmetric multicomponent reactions
    de Graaff, Corien
    Ruijter, Eelco
    Orru, Romano V. A.
    [J]. CHEMICAL SOCIETY REVIEWS, 2012, 41 (10) : 3969 - 4009
  • [28] CeCl3•7H2O Catalyzed C-C and C-N Bond-Forming Cascade Cyclization with Subsequent Side-Chain Functionalization and Rearrangement: A Domino Approach to Pentasubstituted Pyrrole Analogues
    Dhara, Dipankar
    Gayen, Krishnanka S.
    Khamarui, Saikat
    Pandit, Palash
    Ghosh, Sukla
    Maiti, Dilip K.
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 2012, 77 (22) : 10441 - 10449
  • [29] Recent developments in isocyanide based multicomponent reactions in applied chemistry
    Dömling, A
    [J]. CHEMICAL REVIEWS, 2006, 106 (01) : 17 - 89
  • [30] Chemistry and Biology Of Multicomponent Reactions
    Domling, Alexander
    Wang, Wei
    Wang, Kan
    [J]. CHEMICAL REVIEWS, 2012, 112 (06) : 3083 - 3135