Recent advances in the synthesis of pyrroles by multicomponent reactions

被引:656
作者
Estevez, Veronica [1 ]
Villacampa, Mercedes [1 ]
Menendez, J. Carlos [1 ]
机构
[1] Univ Complutense, Fac Farm, Dept Quim Organ & Farmaceut, E-28040 Madrid, Spain
关键词
ONE-POT SYNTHESIS; HIGHLY SUBSTITUTED PYRROLES; PROMOTED 3-COMPONENT REACTION; POLYSUBSTITUTED PYRROLES; 1,3-DICARBONYL COMPOUNDS; FUNCTIONALIZED PYRROLES; PROPARGYLIC ALCOHOLS; CONVENIENT SYNTHESIS; PRIMARY AMINES; EFFICIENT;
D O I
10.1039/c3cs60015g
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Pyrrole is one of the most important one-ring heterocycles. The ready availability of suitably substituted and functionalized pyrrole derivatives is essential for the progress of many branches of science, including biology and materials science. Access to this key heterocycle by multicomponent routes is particularly attractive in terms of synthetic efficiency, and also from the environmental point of view. We update here our previous review on this topic by describing the progress made in this area in the period between mid-2009 and the end of 2013.
引用
收藏
页码:4633 / 4657
页数:25
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