IN VITRO CHARACTERIZATION OF DRUG METABOLIZING ENZYMES AND TRANSPORTERS TO ENABLE A MECHANISTIC DRUG-DRUG INTERACTION ASSESSMENT FOR VENETOCLAX

被引：1
|
作者：
Kikuchi, Ryota [1 ]
Shebley, Mohamad [1 ]
Bow, Daniel A. J. [1 ]
Carr, Robert A. [1 ]
Nijsen, Marjoleen [1 ]
de Morais, Sonia M. [1 ]
机构：
[1] AbbVie Inc, Lake Bluff, IL USA
来源：
DRUG METABOLISM AND PHARMACOKINETICS | 2017年 / 32卷 / 01期
关键词：
D O I：
10.1016/j.dmpk.2016.10.212
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
P86
引用
收藏
页码：S51 / S51
页数：1
相关论文
共 50 条
  • [31] Evaluation of drug-drug interaction of lusutrombopag, a thrombopoietin receptor agonist, via metabolic enzymes and transporters
    Katsube, Takayuki
    Inoue, Yuji
    Fukuhara, Takahiro
    Kano, Takeshi
    Wajima, Toshihiro
    EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2020, 76 (12) : 1659 - 1665
  • [32] A Mechanistic Framework for In Vitro-In Vivo Extrapolation of Liver Membrane Transporters: Prediction of Drug-Drug Interaction Between Rosuvastatin and Cyclosporine
    Jamei, M.
    Bajot, F.
    Neuhoff, S.
    Barter, Z.
    Yang, J.
    Rostami-Hodjegan, A.
    Rowland-Yeo, K.
    CLINICAL PHARMACOKINETICS, 2014, 53 (01) : 73 - 87
  • [33] Drug-drug interaction of cefiderocol, a siderophore cephalosporin, via human drug transporters
    Takayuki Katsube
    Shiro Miyazaki
    Yukitoshi Narukawa
    Martha Hernandez-Illas
    Toshihiro Wajima
    European Journal of Clinical Pharmacology, 2018, 74 : 931 - 938
  • [34] Drug-drug interaction of cefiderocol, a siderophore cephalosporin, via human drug transporters
    Katsube, Takayuki
    Miyazaki, Shiro
    Narukawa, Yukitoshi
    Hernandez-Illas, Martha
    Wajima, Toshihiro
    EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2018, 74 (07) : 931 - 938
  • [35] Expression of drug metabolizing enzymes and transporters in the cochlea: Implications for drug delivery and ototoxicity
    Kennon-McGill, Stefanie
    Clemens, Melissa M.
    McGill, Mitchell R.
    HEARING RESEARCH, 2019, 379 : 98 - 102
  • [36] Brazilian cohort and genes encoding for drug-metabolizing enzymes and drug transporters
    Kim, Vera
    van der Wal, Thijs
    Nishi, Miriam Yumie
    Montenegro, Luciana Ribeiro
    Carrilho, Flair Jose
    Hoshida, Yujin
    Ono, Suzane Kioko
    PHARMACOGENOMICS, 2020, 21 (09) : 575 - 586
  • [37] A Review of CYP-Mediated Drug Interactions: Mechanisms and In Vitro Drug-Drug Interaction Assessment
    Lee, Jonghwa
    Beers, Jessica L.
    Geffert, Raeanne M.
    Jackson, Klarissa D.
    BIOMOLECULES, 2024, 14 (01)
  • [38] Pharmacogenomics of Tamoxifen: Roles of Drug Metabolizing Enzymes and Transporters
    Kiyotani, Kazuma
    Mushiroda, Taisei
    Nakamura, Yusuke
    Zembutsu, Hitoshi
    DRUG METABOLISM AND PHARMACOKINETICS, 2012, 27 (01) : 122 - 131
  • [39] Regulation of drug metabolizing enzymes and transporters in liver disease
    Cherrington, Nathan J.
    DRUG METABOLISM REVIEWS, 2011, 43 : 11 - 11
  • [40] Regulation of drug-metabolizing enzymes and transporters in inflammation
    Aitken, AE
    Richardson, TA
    Morgan, ET
    ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, 2006, 46 : 123 - 149
12345