Synthesis of inherently chiral calixarenes via direct mercuration of the partial cone conformation

被引：20

作者：

Slavik, Petr ^{[1
]}

Kohout, Michal ^{[1
]}

Boehm, Stanislav ^{[1
]}

Eigner, Vaclav ^{[2
]}

Lhotak, Pavel ^{[1
]}

机构：

[1] UCTP, Dept Organ Chem, Tech 5, Prague 16628 6, Czech Republic

[2] Inst Phys AS CR, Vvi, Na Slovance 2, Prague 18221 8, Czech Republic

来源：

CHEMICAL COMMUNICATIONS | 2016年 / 52卷 / 11期

关键词：

SUBSTITUTION;

D O I：

10.1039/c5cc09388k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Direct mercuration of calix[4] arene immobilized in the partial cone conformation led to the meta-substituted isomer which was subsequently subjected to Pd-catalysed coupling (C-H activation) with the neighbouring aromatic subunit. Regioselective mercuration thus enabled access to a novel type of inherently chiral calixarenes with a highly distorted cavity potentially applicable to the design of new chiral receptors.

引用

页码：2366 / 2369

页数：4

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