Analysis of sputum/tracheal aspirate and nasopharyngeal samples for SARS-CoV-2 detection by laboratory-developed test and Panther Fusion system

被引:9
作者
Thwe, Phyu M. [1 ]
Ren, Ping [1 ]
机构
[1] Univ Texas Med Branch, Dept Pathol, Galveston, TX 77555 USA
关键词
SARS-CoV-2; COVID-19; Sputum; Tracheal aspirate; Nasopharyngeal swab sample; Lower respiratory tract;
D O I
10.1016/j.diagmicrobio.2020.115228
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
In this study, 127 sputum/tracheal aspirate specimens were evaluated by a laboratory-developed real-time RTPCR method and Fusion SARS-CoV-2 assay. These specimens were collected from the patients who have nasopharyngeal swab (NPS) samples being used for SARS-CoV-2 detection previously or simultaneously. The overall agreement was 96% between the lower respiratory tract (LRT) and NPS samples, suggesting that LRT specimens could be an option for patients who develop a productive cough or those receiving invasive mechanical ventilation. (C) 2020 Elsevier Inc. All rights reserved.
引用
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页数:4
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