Solid-state IR-LD spectroscopic and theoretical analysis of glycine-containing peptides and their hydrochlorides

被引：46

作者：

Ivanova, Bojidarka B. ^{[1
]}

Kolev, Tsonko

Zareva, Sonya Y.

机构：

[1] Univ Sofia St Kl Ohridsky, Fac Chem, BU-1164 Sofia, Bulgaria

[2] Bulgarian Acad Sci, Inst Organ Chem, BU-1113 Sofia, Bulgaria

来源：

BIOPOLYMERS | 2006年 / 82卷 / 06期

关键词：

glycyl-glycine; glycyl-glycyl-glycine; glycyl-glycyl-glycyl-glycine; protonated forms; peptides; IR-LD spectroscopy; ab initio calculations; solid samples;

D O I：

10.1002/bip.20512

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Aspart of an investigation on the coordination ability of peptides, structural analyses of the solid di-, tri, and tetrapeptides glycyl-glycine (GG), glycyl-glycyl-glycine (GGG), glycyl-glycylg/ycyl-glycine (GGGG), and their protonated hydrochlorides glycyl-glycine center dot HCl (GGH), glycyl-glycyl-glycine center dot HCl (GGGH), and glycyl-glycyl-glycyl-glycine center dot HCl (GGGGH) have been carried out. The quantum chemical calculations (Hartree-Fock/6-31++G**) and linear-dichroic infrared (IR-LD) spectroscopy predict a near to linear structure of the pure ligands, but the experimental IR-LD data are in accordance with a cross-linked disposition of amide fragments in the protonated forms. (c) 2006 Wiley Periodicals, Inc.

引用

页码：587 / 596

页数：10

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